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2-(4-Allyloxyphenyl)ethanehydroxamic acid

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Identification
Molecular formula
C11H13NO3
CAS number
.1106960-91-3
IUPAC name
2-(4-allyloxyphenyl)ethanehydroxamic acid
State
State

At room temperature, 2-(4-Allyloxyphenyl)ethanehydroxamic acid is in a solid state. It is often stored as a dry solid due to potential sensitivity to humidity and atmospheric conditions.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
356.70
Boiling point (Kelvin)
629.85
General information
Molecular weight
221.25g/mol
Molar mass
221.2530g/mol
Density
1.2200g/cm3
Appearence

2-(4-Allyloxyphenyl)ethanehydroxamic acid typically appears as a solid compound. The specific color and texture of the solid can vary depending on the level of purity and form of the sample. High-purity samples may appear as fine, white crystalline powders, though impurities or different crystallization methods can result in off-white or tinted forms.

Comment on solubility

Solubility of 2-(4-allyloxyphenyl)ethanehydroxamic Acid

When exploring the solubility of 2-(4-allyloxyphenyl)ethanehydroxamic acid, it is essential to consider several factors that influence its behavior in various solvents. This compound features a distinctive structural composition that impacts its interaction with solvent molecules. Here are some key points regarding its solubility:

  • Polarity: The presence of the hydroxamic acid functional group enhances the polarity of the compound, likely improving its solubility in polar solvents.
  • Solvent Compatibility: It may show varying degrees of solubility in different solvents:
    • Water: Due to the hydrogen-bonding capacity of the hydroxamic acid group, it is expected to have reasonable solubility.
    • Organic Solvents: Compounds like ethanol and DMSO could facilitate dissolution because of their similar polar characteristics.
  • Influence of Temperature: Increased temperatures might enhance solubility, allowing for better interaction and dissolution rates in specific solvents.

In conclusion, the solubility of 2-(4-allyloxyphenyl)ethanehydroxamic acid is predominantly affected by its *polarity*, *intermolecular interactions*, and *the nature of the solvent used*. Overall, it holds promise for solubility in both polar and some moderately polar solvents, establishing versatile applications in various fields.

Interesting facts

Interesting Facts about 2-(4-allyloxyphenyl)ethanehydroxamic acid

2-(4-allyloxyphenyl)ethanehydroxamic acid is a fascinating compound that showcases the versatility of hydroxamic acids in medicinal chemistry. Here are some engaging insights about this compound:

  • Hydroxamic Acid Family: This compound belongs to the class of hydroxamic acids, which are known for their ability to chelate metal ions. This property is particularly useful in drug design to target metalloproteins.
  • Medicinal Potential: Compounds like 2-(4-allyloxyphenyl)ethanehydroxamic acid have been explored for their *anti-cancer activities*, making them of great interest in pharmaceutical research.
  • Mechanism of Action: The unique structure allows this compound to modulate biological activities, often by inhibiting enzymes that facilitate tumor growth, including histone deacetylases (HDACs).
  • Functional Groups: The incorporation of the allyloxy group enhances the overall reactivity of the molecule, providing potential pathways for further chemical modifications and functionalization.
  • Natural Product Analogues: Some derivatives of hydroxamic acids mimic natural products, offering insights into both traditional and modern medicinal practices.

This compound highlights the intersection of organic chemistry and pharmaceutical development, representing a vital area for exploration in therapeutic applications. As researchers delve deeper into the interactions and behaviors of such compounds, the potential for groundbreaking discoveries continues to expand.

Synonyms
14794-61-7
ACETOHYDROXAMIC ACID, 2-(p-(ALLYLOXY)PHENYL)-
BRN 2725627
2-(p-(Allyloxy)phenyl)acetohydroxamic acid
DTXSID00163846
DTXCID6086337
4-(2-Propenyloxy)benzeneacetohydroxamic acid
N-hydroxy-2-(4-prop-2-enoxyphenyl)acetamide
SCHEMBL12688090