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N-(4-aminobenzoyl)glycine

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Identification
Molecular formula
C9H10N2O3
CAS number
2835-68-9
IUPAC name
2-[(4-aminobenzoyl)amino]acetic acid
State
State

At room temperature, N-(4-aminobenzoyl)glycine is typically in a solid state.

Melting point (Celsius)
232.00
Melting point (Kelvin)
505.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
194.19g/mol
Molar mass
194.1940g/mol
Density
1.4550g/cm3
Appearence

N-(4-aminobenzoyl)glycine appears as colorless to pale yellow crystals or powder. It may also appear off-white depending on the degree of purity and the presence of impurities.

Comment on solubility

Solubility of 2-[(4-aminobenzoyl)amino]acetic acid

2-[(4-aminobenzoyl)amino]acetic acid, with the chemical formula C9H10N2O3, exhibits noteworthy solubility characteristics that are essential for its applications in various fields. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of functional groups such as amino (-NH2) and carboxylic acid (-COOH) enhances its polarity, making it more soluble in polar solvents like water.
  • pH Dependency: The solubility can vary with pH; at certain pH levels, the carboxylic acid may dissociate, increasing solubility due to the formation of charged species.
  • Temperature Effects: Generally, an increase in temperature may increase the solubility of solid compounds in liquids; thus, this compound may show enhanced solubility at elevated temperatures.

It is important to note that while this compound is likely soluble in aqueous solutions due to its polar nature, specific solubility values can be determined experimentally. In practical terms, it can be effectively utilized in formulations that require solubility in biological environments. As highlighted, understanding the solubility profile is crucial for optimizing its application in pharmaceuticals and biochemistry.

Interesting facts

Interesting Facts about 2-[(4-Aminobenzoyl)amino]acetic acid

2-[(4-Aminobenzoyl)amino]acetic acid, also known as a derivative of amino acids, is a fascinating compound that showcases the versatility and complexity of organic chemistry. This compound is not just a simple structure; it serves various important functions and applications in different fields, particularly in medicinal chemistry.

Medical Significance

One of the key properties of this compound is its role in:

  • Pharmaceutical Applications: It can be a potential lead compound in the development of drugs targeted at specific diseases.
  • Research Programs: It is used in biochemical research to study various metabolic pathways.

Structural Highlights

The structure of 2-[(4-aminobenzoyl)amino]acetic acid includes:

  • Amino groups that contribute to its reactivity and ability to form hydrogen bonds.
  • Carboxylic acid functionality, making it an important candidate for proton transfer reactions.

Utility in Chemistry Education

For students and educators, this compound provides an excellent example to explore:

  • Hydrogen bonding and how it influences the stability of molecules.
  • Reaction mechanisms involving amines and carboxylic acids.
  • Functional group transformations in organic synthesis.

As a compound rich in potential, 2-[(4-aminobenzoyl)amino]acetic acid opens avenues for innovative research and discussions in the field of chemistry. Understanding its properties not only enriches academic knowledge but also fosters curiosity towards the vast world of chemical compounds.

Synonyms
4-Aminohippuric acid
aminohippuric acid
61-78-9
P-AMINOHIPPURIC ACID
N-(4-Aminobenzoyl)glycine
para-Aminohippuric acid
Glycine, N-(4-aminobenzoyl)-
Paha
Nefrotest
2-(4-aminobenzamido)acetic acid
N-(p-Aminobenzoyl)glycine
Aminohippurate
para-Aminohippurate
PAH (amino acid)
N-(para-aminobenzoyl)glycine
Hippuric acid, p-amino-
Aminohippurate sodium
p-Aminohippurate
N-(p-Aminobenzoyl)aminoacetic acid
paraaminohippuric acid
2-[(4-aminobenzoyl)amino]acetic acid
4-Amino hippuric acid
PAH
MFCD00007890
NSC 13064
Aminohippuric acid, p-
HSDB 2139
2-[(4-aminophenyl)formamido]acetic acid
4-Aminohippurate
Aminohippuric acid [USP]
EINECS 200-518-9
NSC-13064
Y79XT83BJ9
DTXSID7022590
AI3-52275
CHEBI:104011
Aminohippuric acid (USP)
DTXCID902590
AMINOHIPPURIC ACID [HSDB]
P-AMINOHIPPURIC ACID [MI]
AMINOHIPPURIC ACID [MART.]
AMINOHIPPURIC ACID [USP-RS]
AMINOHIPPURIC ACID [WHO-DD]
N-[(4-aminophenyl)carbonyl]glycine
94-16-6
CAS-61-78-9
NCGC00016279-01
AMINOHIPPURIC ACID [USP MONOGRAPH]
AMINOHIPPURIC ACID (MART.)
AMINOHIPPURIC ACID (USP-RS)
2-((4-aminobenzoyl)amino)acetic acid
N-(p-Aminobenzoyl)aminoacetate
2-((4-aminophenyl)formamido)acetic acid
AMINOHIPPURIC ACID (USP MONOGRAPH)
p Aminohippuric Acid
4 Aminohippuric Acid
para Aminohippuric Acid
SR-05000002048
UNII-Y79XT83BJ9
4-Aminohippuricacid
4Aminohippuric acid
4-aminohippuric-acid
Hippuric acid, pamino
N(pAminobenzoyl)glycine
Spectrum_001310
(p-Aminobenzoyl)glycine
N(4Aminobenzoyl)glycine
(4-aminobenzoyl)glycine
Prestwick0_000895
Prestwick1_000895
Prestwick2_000895
Prestwick3_000895
Spectrum2_001515
Spectrum3_000952
Spectrum4_001065
Spectrum5_001100
N(paraAminobenzoyl)glycine
CHEMBL463
Glycine, N(4aminobenzoyl)
Oprea1_490712
BSPBio_000710
KBioGR_001390
KBioSS_001790
MLS002154055
DivK1c_000694
SCHEMBL196513
SPECTRUM1503069
SPBio_001589
SPBio_002919
BPBio1_000782
GTPL4810
p-Aminohippuric acid, >=99%
N(pAminobenzoyl)aminoacetic acid
Hippuric acid, p-amino-(8CI)
4-Aminohippuric acid (Standard)
HMS502C16
HY-B1306R
KBio1_000694
KBio2_001790
KBio2_004358
KBio2_006926
KBio3_002044
NSC7550
NINDS_000694
HMS1570D12
HMS1922C07
HMS2092H18
HMS2097D12
HMS2233A21
HMS3373E19
HMS3651L04
HMS3714D12
Pharmakon1600-01503069
ALBB-025851
BCP04299
HY-B1306
NSC-7550
NSC13064
4-AMINOHIPPURIC ACID BIOTECH
Tox21_110345
BBL027666
CCG-39181
NSC758232
s2883
STK801822
[(4-Aminobenzoyl)amino]acetic acid #
AKOS000120722
Tox21_110345_1
CS-4816
DB00345
FA16039
NSC-758232
IDI1_000694
p-Aminohippuric acid, >=98.0% (T)
NCGC00016279-02
NCGC00016279-03
NCGC00016279-05
NCGC00094993-01
NCGC00094993-02
AC-29237
SMR001233372
SY048511
SBI-0051760.P002
DB-053989
A0313
AB00052309
NS00014737
SW197249-3
EN300-20920
7E-944
D06890
D88242
N-(4-Aminobenzoyl)glycine;p-Aminohippuric acid
AB00052309_08
Q291271
SR-05000002048-1
SR-05000002048-3
BRD-K65544384-001-14-1
BRD-K65544384-001-15-8
BRD-K65544384-236-01-0
BRD-K65544384-236-02-8
BRD-K65544384-236-03-6
Z104484866
Aminohippuric acid, United States Pharmacopeia (USP) Reference Standard
200-518-9
ZWD