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Benzhydrylamine

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Identification
Molecular formula
C13H14N2
CAS number
1164-16-5
IUPAC name
2-[(4-aminophenyl)methyl]aniline
State
State

At room temperature, benzhydrylamine is typically in a solid state.

Melting point (Celsius)
49.50
Melting point (Kelvin)
322.70
Boiling point (Celsius)
364.60
Boiling point (Kelvin)
637.80
General information
Molecular weight
184.27g/mol
Molar mass
184.2580g/mol
Density
1.1490g/cm3
Appearence

Benzhydrylamine is a white to pale yellow crystalline solid. It typically forms in needle-like crystals. Being aromatic, it may have a faint amine-like odor.

Comment on solubility

Solubility of 2-[(4-aminophenyl)methyl]aniline

2-[(4-aminophenyl)methyl]aniline, a substituted aniline compound, exhibits specific solubility characteristics that are important for its applications.

Properties Affecting Solubility:

Several factors play a role in the solubility of this compound:

  • Functional Groups: The amino group (-NH2) present in the molecular structure can engage in hydrogen bonding, which may enhance solubility in polar solvents.
  • Molecular Weight: Its moderate molecular weight contributes to its overall solubility profile, allowing it to dissolve adequately in certain solvents.
  • Hydrophobic Character: The aromatic rings present can contribute to hydrophobic interactions, influencing solubility in non-polar solvents.

General Solubility Trends:

In general, it can be observed that:

  • Solubility in Water: 2-[(4-aminophenyl)methyl]aniline has limited solubility in water due to its hydrophobic nature.
  • Solubility in Organic Solvents: This compound is more soluble in organic solvents such as ethanol, acetone, and dichloromethane, where the interactions are more favorable.

As a practical takeaway, understanding the solubility of 2-[(4-aminophenyl)methyl]aniline can provide valuable insight into its use in various chemical processes and formulations. The solubility behavior can significantly influence its reactivity and availability in synthetic applications.

Interesting facts

Interesting Facts about 2-[(4-aminophenyl)methyl]aniline

2-[(4-aminophenyl)methyl]aniline, commonly known in scientific circles for its unique structural characteristics, is an intriguing compound with a variety of applications and properties:

  • Structural Complexity: The compound contains both an amino and an aniline group, which makes it a valuable intermediate in organic synthesis. The arrangement of these functional groups enables diverse chemical reactivity.
  • Applications in Dyes: Often utilized in the production of azo dyes, 2-[(4-aminophenyl)methyl]aniline serves as a dye precursor, showcasing vibrant colors and stability.
  • Pharmaceutical Importance: Given the presence of the amine group, this compound has potential roles in medicinal chemistry, acting as a building block for drug development targeting various biological pathways.
  • Toxicological Considerations: While it exhibits significant utility, 2-[(4-aminophenyl)methyl]aniline must be handled with care due to the potential toxicity of amine compounds and their derivatives.
  • Research Applications: It has been the subject of research related to its interaction with proteins and enzymes, making it a compound of interest for biochemists studying enzyme inhibition and catalysis.

Scientists are often fascinated by the dual nature of compounds like 2-[(4-aminophenyl)methyl]aniline, which can be both useful and hazardous. As one researcher pointed out, "Understanding the balance between a compound's application and its risks is crucial in the field of chemistry."
This compound serves as a reminder of the intricate relationship between chemical structure and functional utility.

Synonyms
2-(4-aminobenzyl)aniline
1208-52-2
2,4'-Diaminodiphenylmethane
2,4'-METHYLENEDIANILINE
2,4'-Diaminodiphenylmethan
2-((4-Aminophenyl)methyl)benzenamine
HSDB 6020
benzenamine, 2-[(4-aminophenyl)methyl]-
UNII-VH1ZAZ44QJ
Benzenamine, 2-((4-aminophenyl)methyl)-
EINECS 214-900-8
2,4'-Diaminodiphenylmethan [German]
BRN 2100903
2,4'-methylenediphenylamine
DTXSID9051616
2-13-00-00110 (Beilstein Handbook Reference)
2-[(4-Aminophenyl)methyl]benzenamine
2,4'-DIAMINODIPHENYLMETHAN (GERMAN)
o,p'Diaminodiphenylmethane
2,4'Diaminodiphenylmethan
2,4'diaminodiphenylmethane
2,4'Diphenylmethanediamine
Aniline, 2,4'methylenedi
2,4'Methylenebis(aniline)
2',4Bis(aminophenyl)methane
DTXCID0030168
2((4Aminophenyl)methyl)benzenamine
2,4'-MDA
2((4Aminophenyl)methyl)benzeneamine
Benzenamine, 2((4aminophenyl)methyl)
inchi=1/c13h14n2/c14-12-7-5-10(6-8-12)9-11-3-1-2-4-13(11)15/h1-8h,9,14-15h
2',4-Bis(aminophenyl)methane
2-[(4-aminophenyl)methyl]aniline
2,4'-Diphenylmethanediamine
2,4'-Methylenebis(aniline)
o,p'-Diaminodiphenylmethane
Aniline, 2',4-methylenedi-
2-((4-Aminophenyl)methyl)benzeneamine
VH1ZAZ44QJ
Aniline, 2,4'-methylenedi-
4-[(2-aminophenyl)methyl]aniline
MFCD01670227
SCHEMBL39484
2,4'-diamino-diphenylmethane
2-(4-aminobenzyl)benzenamine
YSSJ00835
UTNMPUFESIRPQP-UHFFFAOYSA-N
AKOS006278431
CS-W019351
FA46605
DS-18290
NS00020258
2',4-BIS(AMINOPHENYL)METHANE [HSDB]
C71726
EN300-2889203
Q27291828