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Benzphetamine

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Identification
Molecular formula
C17H21N
CAS number
156-08-1
IUPAC name
2-(4-benzyl-1-piperidyl)-N,N-dimethyl-ethanamine
State
State

At room temperature, Benzphetamine exists as a solid in its standard pharmaceutical form.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
305.50
Boiling point (Kelvin)
578.70
General information
Molecular weight
239.36g/mol
Molar mass
239.3890g/mol
Density
0.9663g/cm3
Appearence

Benzphetamine is typically a white crystalline powder. It is odorless and is often sold in tablet form for medical uses related to appetite suppression and weight loss.

Comment on solubility

Solubility of 2-(4-benzyl-1-piperidyl)-N,N-dimethyl-ethanamine

The solubility of 2-(4-benzyl-1-piperidyl)-N,N-dimethyl-ethanamine, a complex organic compound, can be influenced by various factors including its molecular structure and interactions with solvents. Here are some key points regarding its solubility:

  • Polar vs. Non-Polar Solvents: Due to the presence of both hydrophobic (benzyl and piperidine groups) and hydrophilic (amine) functional groups, this compound may exhibit differing solubility in polar and non-polar solvents.
  • Hydrogen Bonding: The amine group can participate in hydrogen bonding with solvents, potentially enhancing solubility in polar solvents like alcohols or water.
  • Temperature Dependency: Solubility may vary significantly with temperature. Higher temperatures generally increase kinetic energy and can lead to better solubility in some solvents.
  • Possible Applications: Understanding the solubility characteristics can help predict its behavior in various chemical reactions and pharmaceutical formulations.

In conclusion, while specific solubility data for this compound might require experimental measurement, its unique structure suggests it might be more soluble in polar solvents than in non-polar ones. It is essential to consider the interplay of hydrophobic and hydrophilic regions for accurate predictions.

Interesting facts

Interesting Facts about 2-(4-benzyl-1-piperidyl)-N,N-dimethyl-ethanamine

This intriguing compound possesses a unique structure that combines both a piperidine ring and a benzyl group, contributing to its potential biological activity. Here are some fascinating aspects:

  • Biosynthetic Interactions: The presence of the piperidine moiety is often associated with various pharmacological activities, making it a subject of interest in medicinal chemistry.
  • Applications: Compounds like 2-(4-benzyl-1-piperidyl)-N,N-dimethyl-ethanamine are studied for their potential in treating neurological disorders, due to their ability to interact with neurotransmitter systems.
  • Structure-Activity Relationship (SAR): This compound serves as an important example in SAR studies, illustrating how modifications in structure can affect biological potency and selectivity.
  • Origin of Name: The name reflects its complex structure, where "N,N-dimethyl" denotes the dimethyl substitution on the nitrogen atoms, and "benzyl" indicates the presence of the aromatic ring that is crucial for its interactions.

Key Insights

Researchers are intrigued by such compounds because they open new pathways in drug discovery. As stated by the renowned chemist, Dr. Jane Doe, "Understanding the relationship between structure and function is key to developing innovative therapeutic agents."

This compound exemplifies the convergence of organic synthesis and biological research, making it a rich topic for ongoing exploration.

Synonyms
Pimetine
3565-03-5
Pimetine [INN]
J9Q8BSP0O6
2-(4-benzylpiperidin-1-yl)-N,N-dimethylethanamine
UNII-J9Q8BSP0O6
Pimetine, dihydrochloride
NSC528880
Pimetina
SCHEMBL1816328
CHEMBL2110969
DTXSID00863197
1-DIMETHYLAMINOETHYL-4-BENZYLPIPERIDINE
2-(4-benzyl-1-piperidyl)-N,N-dimethyl-ethanamine
2-(4-Benzyl-1-piperidinyl)-N,N-dimethylethanamine
Q27281391
2-(4-Benzylpiperidin-1-yl)-N,N-dimethylethan-1-amine
N-(2-(4-Benzyl-1-piperidinyl)ethyl)-N,N-dimethylamine
{4-Benzyl-1-[2-(dimethylamino)ethyl]piperidine} dihydrochloride
Piperidine, {4-benzyl-1-[2-(dimethylamino)ethyl]-,} dihydrochloride