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Benzylpiperazine derivative

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Identification
Molecular formula
C20H26N2O4
CAS number
82677-80-9
IUPAC name
2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone
State
State

The compound is a solid at room temperature.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.15
Boiling point (Celsius)
427.60
Boiling point (Kelvin)
700.80
General information
Molecular weight
326.41g/mol
Molar mass
326.4140g/mol
Density
1.3000g/cm3
Appearence

The compound typically appears as a crystalline solid with a white to off-white coloration.

Comment on solubility

Solubility of 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone

The solubility of 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone can be complex due to its structural characteristics. This organic compound exhibits a variety of interactions based on its molecular makeup. Here are some key points regarding its solubility:

  • Solvent Dependency: The solubility is greatly influenced by the choice of solvent. It tends to dissolve well in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), while showing limited solubility in water.
  • Hydrophobic and Hydrophilic Balance: The presence of multiple methoxy groups contributes to some hydrophilic character, but the overall structure remains largely hydrophobic, affecting its tendencies to dissolve.
  • pH Influence: The solubility might also be affected by the pH of the environment, as the piperazine moiety can interact with acids and bases, potentially leading to ionization in acidic or basic conditions.

In summary, the solubility profile of this compound is highly specific to its environment and solvent interactions. Knowing these nuances can help in optimizing its use in various chemical applications. Always consider performing solubility experiments under controlled conditions to ascertain the precise behavior of the compound in desired scenarios.

Interesting facts

Interesting Facts about 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone

2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone is a fascinating compound that has drawn interest in various fields of study. Here are some noteworthy points:

  • Structural Complexity: This compound boasts a unique structure featuring both a piperazine ring and a phenyl moiety, indicating potential interactions with multiple biological targets. The presence of trimethoxy groups adds to its molecular diversity.
  • Potential Pharmacological Activity: Due to its structural components, it is often investigated for its role in neuropharmacology. Compounds with similar structures have been known to exhibit anxiolytic or antidepressant properties.
  • Research Applications: Scientists have explored its applications in medicinal chemistry, especially concerning drug design for conditions such as anxiety and depression, making it a significant compound within therapeutic investigations.
  • Analog Studies: The modifications in the piperazine and phenyl sections often serve as a base for synthesizing analogs with varying properties, aiding in understanding structure-activity relationships.

As the field of chemistry continues to advance, the exploration of compounds like 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone highlights the intricate connections between molecular structure and biological function. It stands as a reminder of the endless possibilities that await within synthetic and medicinal chemistry.