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Dibenzylpiperazine

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Identification
Molecular formula
C20H26Cl2N2O3
CAS number
1786-81-8
IUPAC name
2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone;dihydrochloride
State
State

At room temperature, this compound is typically found in a solid state. It is supplied as a dihydrochloride salt, which is generally stable under normal conditions and has better solubility in water compared to its base form.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
388.35g/mol
Molar mass
388.3500g/mol
Density
1.2000g/cm3
Appearence

The compound usually appears as a crystalline solid and is often furnished in white to off-white color. Due to its salt form as a dihydrochloride, it is often quite hygroscopic.

Comment on solubility

Solubility of 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone; dihydrochloride

The solubility of 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone; dihydrochloride is a critical aspect for its application in chemical and pharmaceutical contexts. This compound can exhibit different solubility behaviors depending on various factors:

  • Polar nature: The presence of the dihydrochloride salt form suggests enhanced solubility in polar solvents, particularly water.
  • Solvent interactions: Organic solvents like methanol or ethanol may also facilitate dissolution due to the compound's structure.
  • Temperature dependence: Increasing temperature can often increase solubility for many compounds.

It's important to note:

  1. Solubility varies greatly: The exact solubility of this specific compound may vary and should be determined experimentally.
  2. Concentration impact: As concentration increases, solubility could reach a saturation point, above which precipitation might occur.

In summary, for practical applications involving 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone; dihydrochloride, it is vital to assess solubility conditions carefully to achieve desired outcomes in formulations.

Interesting facts

Interesting Facts about 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone; dihydrochloride

This compound, a derivative of piperazine, presents a fascinating case in medicinal chemistry, especially due to its potential applications in pharmacology. Here are some engaging insights:

  • Structural Significance: The compound features a unique integration of a piperazine ring and a phenyl group with trimethoxy substituents, which contribute to its biological activities. The presence of these functional groups can significantly influence the compound's interactions with various biological pathways.
  • Biological Activity: Research indicates that compounds like this one may exhibit interesting psychoactive properties. The benzylpiperazine moiety is often associated with effects on serotonin and dopamine receptors, hinting at use in neurological treatments.
  • Synthesis Opportunities: Synthetic routes to produce this compound typically involve multiple steps, which provide a practical laboratory exercise for students in organic chemistry. It encourages the exploration of reaction mechanisms and the application of various synthetic techniques.
  • Research Potential: The compound presents a promising avenue for developing new drugs due to its complex structure. Researchers are constantly on the lookout for similar compounds that can lead to breakthroughs in treating mental health disorders.
  • Analog Studies: Studying analogs of this compound can reveal critical insights into structure-activity relationships (SAR). Variations in the substituted groups can lead to a wide range of pharmacological profiles.

In summary, 2-(4-benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanone; dihydrochloride emerges as more than just a chemical entity; it symbolizes the convergence of _innovation_ and _application_ in drug discovery. As chemistry students explore its properties and potential, they play a role in the future of medicine.

Synonyms
17837-65-9
1-Benzyl-4-(3,4,5-trimethoxybenzoylmethyl)piperidine dihydrochloride
ACETOPHENONE, 1-(4-BENZYLPIPERAZINYL)-3',4',5'-TRIMETHOXY-, DIHYDROCHLORIDE
DTXSID10170465
1-(4-Benzylpiperazinyl)-3',4',5'-trimethoxyacetophenone dihydrochloride
Piperidine, 1-benzyl-4-(3,4,5-trimethoxybenzoylmethyl)-, dihydrochloride
DTXCID0092956
2-(4-Benzyl-1-piperazinyl)-1-(3,4,5-trimethoxyphenyl)ethanone dihydrochloride
2-(4-Benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)ethanonedihydrochloride