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2-[4-bromo-2-(diethylaminomethyl)phenoxy]acetohydrazide

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Identification
Molecular formula
C13H19BrN2O2
CAS number
102886-98-4
IUPAC name
2-[4-bromo-2-(diethylaminomethyl)phenoxy]acetohydrazide
State
State

The compound exists in a solid state at room temperature, generally as a crystalline solid. It is stable under normal conditions of storage and use.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
393.00
Boiling point (Kelvin)
666.15
General information
Molecular weight
330.21g/mol
Molar mass
330.2390g/mol
Density
1.3700g/cm3
Appearence

The compound appears as a crystalline powder, usually white to off-white in color. It may vary in appearance depending on the purity and form (such as amorphous or crystalline) of the sample.

Comment on solubility

Solubility of 2-[4-bromo-2-(diethylaminomethyl)phenoxy]acetohydrazide

The solubility of 2-[4-bromo-2-(diethylaminomethyl)phenoxy]acetohydrazide in various solvents can provide insights into its chemical behavior and potential applications. Generally, the solubility of such compounds can be influenced by the following factors:

  • Polarity of the solvent: Compounds with polar functional groups tend to dissolve better in polar solvents like water or methanol.
  • Hydrophobic and hydrophilic balance: The presence of bulky or hydrophobic groups can limit solubility in polar mediums.
  • Temperature: Higher temperatures often enhance solubility for solid compounds.

For this particular compound, one might expect a moderate solubility profile due to:

  • The presence of the diethylaminomethyl group, which can increase solubility in certain organic solvents.
  • The phenoxy moiety, which may also affect interactions with solvents due to its aromatic nature.
  • The bromo substituent, which could add to the steric hindrance affecting solubility.

In summary, while specific solubility data has not been provided, it would be prudent to consider solubility testing in both polar and non-polar solvents to ascertain the best conditions for its use in various chemical applications. The interplay of its molecular structure suggests that 2-[4-bromo-2-(diethylaminomethyl)phenoxy]acetohydrazide may exhibit interesting and varied solubility characteristics across different environments.

Interesting facts

Interesting Facts about 2-[4-bromo-2-(diethylaminomethyl)phenoxy]acetohydrazide

2-[4-bromo-2-(diethylaminomethyl)phenoxy]acetohydrazide is a fascinating compound that has garnered attention in both chemical research and potential therapeutic applications. Below are some intriguing insights into this compound:

  • Dual Functional Groups: This compound features both an acetohydrazide moiety and a bromo-substituted phenoxy structure, which makes it a versatile scaffold for further chemical modifications.
  • Pharmacological Potential: Compounds with hydrazide linkages have been studied for their biological activities, including potential use as anti-cancer agents. The presence of the diethylaminomethyl group may enhance its interaction with biological targets.
  • Electrophilic Character: The bromine atom in the compound can act as a leaving group in nucleophilic substitution reactions, making it an excellent candidate for further derivatization.
  • Synthetic Pathways: This compound can be synthesized through multiple synthetic routes, allowing for the creation of various analogs. Students and chemists find this flexibility in synthesis to be particularly appealing.
  • Research Applications: Due to its unique structure, this compound is of interest in fields such as medicinal chemistry, where researchers explore its potential as a lead compound for drug development.

As a chemist, encountering compounds like 2-[4-bromo-2-(diethylaminomethyl)phenoxy]acetohydrazide broadens our understanding of chemical reactivity and potential applications. This compound exemplifies the importance of modifying well-established structures to innovate and discover new therapeutic avenues.

Synonyms
16158-14-8
ACETIC ACID, ((4-BROMO-alpha-(DIETHYLAMINO)-o-TOLYL)OXY)-, HYDRAZIDE
(4-Bromo-2-((diethylamino)methyl)phenoxy)-acetic acid hydrazide
BRN 2869704
Acetic acid, (4-bromo-2-((diethylamino)methyl)phenoxy)-, hydrazide
YV85VQD35C
DTXSID20167200
2-[4-Bromo-2-[(diethylamino)methyl]phenoxy]acetic acid hydrazide
Bromo-2-((diethylamino)methyl)phenoxy)-acetic acid hydrazide, (4-
Acetic acid, 2-[4-bromo-2-[(diethylamino)methyl]phenoxy]-, hydrazide