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2-[4-bromo-2-(morpholinomethyl)phenoxy]acetohydrazide

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Identification
Molecular formula
C13H17BrN2O3
CAS number
959000-41-4
IUPAC name
2-[4-bromo-2-(morpholinomethyl)phenoxy]acetohydrazide
State
State

This compound is typically a solid at room temperature.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
472.50
Boiling point (Kelvin)
745.70
General information
Molecular weight
331.19g/mol
Molar mass
331.1910g/mol
Density
1.5728g/cm3
Appearence

The compound typically appears as a white to off-white powder or crystalline solid. Its appearance is characteristic of many organic brominated compounds, which may also impart a slight yellowish tint depending on purity and the presence of impurities.

Comment on solubility

Solubility of 2-[4-bromo-2-(morpholinomethyl)phenoxy]acetohydrazide

The solubility of 2-[4-bromo-2-(morpholinomethyl)phenoxy]acetohydrazide is an interesting aspect of its chemical properties. Generally, the solubility of a compound can depend on several factors, including polarity, molecular structure, and the presence of functional groups. Here’s a breakdown of what might influence its solubility:

  • Polarity: Compounds with polar functional groups tend to have higher solubility in polar solvents. Since this compound contains a morpholinomethyl group, which is polar, it may exhibit enhanced solubility in polar solvents like water.
  • Hydrogen Bonding: The presence of amide functional groups can lead to strong hydrogen bonding interactions with solvent molecules, further influencing solubility. In this case, the hydrazide moiety may contribute to solubility in various solvents.
  • Hydrophobic Interactions: On the other hand, the bromo group and the large aromatic systems can introduce hydrophobic characteristics, which might limit solubility in polar solvents.
  • Temperature Effects: As with many solid compounds, solubility may increase with temperature, making it essential to consider conditions when evaluating dissolution properties.

In summary, the solubility of 2-[4-bromo-2-(morpholinomethyl)phenoxy]acetohydrazide could be described as a complex interplay of its structural features and environmental conditions. Understanding the specific solubility can enhance its practical applications and effectiveness in various chemical contexts.

Interesting facts

Interesting Facts about 2-[4-Bromo-2-(Morpholinomethyl)phenoxy]acetohydrazide

This intriguing compound, 2-[4-bromo-2-(morpholinomethyl)phenoxy]acetohydrazide, has drawn interest in the field of medicinal chemistry due to its potential as a therapeutic agent. Here are some engaging aspects of this compound:

  • Multifunctional Potential: The presence of a hydrazide functional group in the molecule is notable. Hydrazides have been widely studied for their antimicrobial, anti-inflammatory, and anticancer properties.
  • Unique Structural Features: The bromo group and morpholino chain significantly influence the compound's biological activity. The bromine's electron-withdrawing nature can increase the compound’s reactivity, while the morpholine ring may enhance its solubility and facilitate interaction with biological targets.
  • Applications in Drug Development: Due to its structural characteristics, this compound might serve as a lead compound in the development of new drugs, potentially targeting various diseases. Research into similar compounds has yielded promising results in the pharmaceutical industry.
  • Synthetic Versatility: The synthetic route to create this compound can be an excellent demonstration of various organic chemistry techniques, including nucleophilic substitutions and hydrazone formation, making it a valuable compound for students to study in advanced organic synthesis.
  • Research Opportunities: This compound presents a fascinating opportunity for researchers. Further studies could explore its biological effects, mechanism of action, and possible modifications to enhance its therapeutic efficacy.

In conclusion, 2-[4-bromo-2-(morpholinomethyl)phenoxy]acetohydrazide stands as a promising candidate in the realm of medicinal chemistry, illustrating how detailed knowledge of structure can lead to significant advancements in therapeutic applications. The ongoing exploration of its properties paves the way for potential breakthroughs in drug development.

Synonyms
16158-23-9
ACETIC ACID, ((4-BROMO-alpha-MORPHOLINO-o-TOLYL)OXY)-, HYDRAZIDE
BRN 0822460
(4-Bromo-2-(4-morpholinylmethyl)phenoxy)acetic acid hydrazide
Acetic acid, (4-bromo-2-(4-morpholinylmethyl)phenoxy)-, hydrazide
TAT92X5A7Q
DTXSID40167202
2-[4-Bromo-2-(4-morpholinylmethyl)phenoxy]acetic acid hydrazide
Bromo-2-(2-(4-morpholinylmethyl)phenoxy)acetic acid hydrazide, (4-
(4-BROMO-2-(2-(4-MORPHOLINYLMETHYL)PHENOXY)ACETIC ACID HYDRAZIDE
Acetic acid, 2-[4-bromo-2-(4-morpholinylmethyl)phenoxy]-, hydrazide