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Brompheniramine

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Identification
Molecular formula
C16H19BrClNO
CAS number
86-22-6
IUPAC name
2-[(4-bromophenyl)-phenyl-methoxy]ethyl-dimethyl-ammonium;chloride
State
State

At room temperature, Brompheniramine is solid, typically in the form of crystalline powder.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.15
Boiling point (Celsius)
323.00
Boiling point (Kelvin)
596.15
General information
Molecular weight
319.69g/mol
Molar mass
319.2490g/mol
Density
1.0860g/cm3
Appearence

Brompheniramine is typically seen as a white or off-white crystalline powder. This compound is known for its crystalline nature, which might appear as soft aggregates or finer crystals depending on its preparation method.

Comment on solubility

Solubility of 2-[(4-bromophenyl)-phenyl-methoxy]ethyl-dimethyl-ammonium;chloride

The solubility of 2-[(4-bromophenyl)-phenyl-methoxy]ethyl-dimethyl-ammonium chloride can be quite intriguing due to its chemical structure and the nature of its components. This compound, which features both hydrophobic and hydrophilic elements, can exhibit varying solubility characteristics depending on several factors. Here are some points to consider:

  • Polarity: The presence of the ammonium group can enhance solubility in polar solvents, while the bromophenyl and phenyl moieties contribute to hydrophobic interactions.
  • Solvent Choice: This compound is likely to be more soluble in polar solvents like water compared to non-polar solvents due to the ionic nature of the chloride counterion.
  • Temperature Effects: Solubility may increase with temperature; hence, higher temperatures could favor dissolution of the compound in solvent.
  • Concentration: At higher concentrations, solubility limits may be reached, leading to precipitation if the solvent cannot accommodate additional solute.

Generally, ammonium salts, such as this compound, are known to be soluble in water, but the specific solubility should be empirically determined for definitive applications. As with many compounds, "the devil is in the details," and experimental conditions can dramatically influence solubility behavior.

Interesting facts

Interesting Facts about 2-[(4-bromophenyl)-phenyl-methoxy]ethyl-dimethyl-ammonium;chloride

This fascinating compound, known for its dual functionality, plays a significant role in various fields, including medicinal chemistry and material science. Here are some intriguing insights:

  • Quaternary Ammonium Ion: This compound contains a quaternary ammonium structure, which enhances its stability and solubility in polar solvents. This characteristic is essential for many applications in which ionic interactions are crucial.
  • Use in Antimicrobial Agents: Compounds of this nature often exhibit antimicrobial properties, making them potential candidates for disinfectants and antiseptics. Many studies explore the efficacy of quaternary ammonium compounds in controlling microbial growth.
  • Role in Nanotechnology: The unique molecular structure can be harnessed in the synthesis of nanoparticles. The presence of bromine in the structure adds an interesting aspect, as brominated compounds can influence the properties of nanoparticles, such as their reactivity and stability.
  • Drug Design Implications: The ability of such compounds to interact with biological membranes suggests potential use in drug delivery systems. Their amphiphilic nature may help facilitate the transport of therapeutic agents across lipid membranes.
  • Synthetic Pathways: The synthesis of this compound involves intricate organic reactions, showcasing the importance of understanding reaction mechanisms in organic chemistry, and expanding on techniques such as nucleophilic substitution and electrophilic aromatic substitution.

In summary, 2-[(4-bromophenyl)-phenyl-methoxy]ethyl-dimethyl-ammonium;chloride is not just a chemical entity; it embodies a multitude of applications and research opportunities. Its complex structure and properties open doors to innovations in various scientific domains.

Synonyms
2-[(4-bromophenyl)-phenylmethoxy]ethyl-dimethylazanium;chloride
2-((4-Bromophenyl)phenylmethoxy)ethyl(dimethyl)ammonium chloride
Bromanyl (TN)
Diphenhydramine Impurity C hydrochloride
1808-12-4 (HCl)
NS00082892
D03166