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2-(4-bromophenyl)acetohydrazide

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Identification
Molecular formula
C8H9BrN2O
CAS number
16748-20-4
IUPAC name
2-(4-bromophenyl)acetohydrazide
State
State

At room temperature, 2-(4-bromophenyl)acetohydrazide is a solid compound, usually in crystalline form.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
276.20
Boiling point (Kelvin)
549.35
General information
Molecular weight
241.08g/mol
Molar mass
241.0810g/mol
Density
1.4512g/cm3
Appearence

2-(4-bromophenyl)acetohydrazide typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(4-bromophenyl)acetohydrazide

2-(4-bromophenyl)acetohydrazide exhibits interesting solubility characteristics, which can be understood by exploring its interactions with various solvents. Generally, its solubility can be summarized as follows:

  • Polar solvents: This compound shows a fair degree of solubility in polar solvents such as water and methanol. The presence of the hydrazide functional group enhances its solvation due to hydrogen bonding.
  • Non-polar solvents: In contrast, 2-(4-bromophenyl)acetohydrazide is less soluble in non-polar solvents, such as hexane or toluene. The non-polar characteristics of these solvents do not favor the dissolution of the polar components of the compound.
  • Temperature dependence: The solubility of 2-(4-bromophenyl)acetohydrazide is also likely to vary with temperature, as is common with many organic compounds. Increasing temperature typically enhances solubility in most solvents.

In conclusion, the solubility of 2-(4-bromophenyl)acetohydrazide is governed primarily by the polarity of the solvent used. As a general rule, it is more soluble in polar environments compared to non-polar ones. Understanding these behaviors is essential for applications in pharmaceutical formulations and organic synthesis.

Interesting facts

Interesting Facts about 2-(4-Bromophenyl)acetohydrazide

2-(4-Bromophenyl)acetohydrazide is a fascinating compound with several noteworthy attributes that excite both chemists and students alike. Known for its unique structure and properties, it offers insights into various chemical applications. Here are some interesting aspects:

  • Functional Groups: The presence of both the hydrazide and bromophenyl groups makes this compound interesting for the study of reactivity and synthesis. Its functional groups can participate in a range of chemical reactions, including nucleophilic substitutions and condensation reactions.
  • Medicinal Chemistry: Compounds like 2-(4-bromophenyl)acetohydrazide are often explored in medicinal chemistry for potential therapeutic applications. Variants of hydrazides have exhibited biological activity, making them candidates for drug development.
  • Research Importance: This compound is used in research to develop new materials and pharmaceuticals. Its ability to form derivatives opens the door for potentially discovering new compounds with desirable biological properties.
  • Synthetic Pathways: The synthesis of 2-(4-bromophenyl)acetohydrazide typically involves straightforward reactions, making it an excellent candidate for educational purposes when teaching organic synthesis.

As chemists delve deeper into the world of hydrazides, compounds like 2-(4-bromophenyl)acetohydrazide serve as key players in both theoretical exploration and practical application. Its versatile reactivity not only expands our understanding of organic chemistry but also inspires innovative chemical research.

Synonyms
2-(4-bromophenyl)acetohydrazide
57676-50-3
MFCD02612352
BRN 3129728
Oprea1_792152
SCHEMBL12941833
DTXSID00932695
ALBB-001041
BBL015374
STK066737
AKOS000150900
2-(4-Bromophenyl)ethanehydrazonic acid
SB86132
VS-04936
CS-0206005
ST50828570
F78385
2-15-00-00164 (Beilstein Handbook Reference)