Skip to main content

2-(4-bromophenyl)indane-1,3-dione

ADVERTISEMENT
Identification
Molecular formula
C15H9BrO2
CAS number
1147-63-9
IUPAC name
2-(4-bromophenyl)indane-1,3-dione
State
State

At room temperature, 2-(4-bromophenyl)indane-1,3-dione exists as a solid. It has a firm crystalline structure that is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
118.70
Melting point (Kelvin)
391.85
Boiling point (Celsius)
335.80
Boiling point (Kelvin)
608.95
General information
Molecular weight
303.14g/mol
Molar mass
303.1190g/mol
Density
1.4678g/cm3
Appearence

The compound 2-(4-bromophenyl)indane-1,3-dione typically presents itself as a crystalline solid. Its appearance is characterized by a white to off-white coloration.

Comment on solubility

Solubility of 2-(4-bromophenyl)indane-1,3-dione

The solubility of 2-(4-bromophenyl)indane-1,3-dione in various solvents provides insight into its chemical behavior and potential applications. This compound displays distinct solubility characteristics that can be summarized as follows:

  • Organic Solvents: 2-(4-bromophenyl)indane-1,3-dione is generally soluble in common organic solvents such as dimethyl sulfoxide (DMSO), dimethylformamide (DMF), and ethyl acetate. Its aromatic structure often enhances its solubility in non-polar to moderately polar solvents.
  • Aqueous Solubility: This compound is typically not soluble in water due to its hydrophobic nature brought by the bulky indane and bromophenyl groups, which inhibit the formation of hydrogen bonds with water molecules.
  • Temperature Dependence: In some instances, increased temperature can improve solubility in organic solvents. Heating may help to overcome intermolecular forces, allowing for a greater dissolution of the compound.

In summary, while 2-(4-bromophenyl)indane-1,3-dione exhibits good solubility in various organic solvents, its limited solubility in water restricts its use in aqueous environments. Understanding these solubility properties is crucial for optimizing reactions and formulations involving this compound.

Interesting facts

Interesting Facts about 2-(4-bromophenyl)indane-1,3-dione

2-(4-bromophenyl)indane-1,3-dione is a notable compound that belongs to the family of indanediones, which are known for their diverse applications in various fields of chemistry and materials science. Here are some engaging insights about this intriguing compound:

  • Fluorescence and Photocleavage: Compounds like 2-(4-bromophenyl)indane-1,3-dione are studied for their fluorescent properties, which make them useful in applications such as molecular probes and photolabeling.
  • Biological Activity: Some derivatives of indanedione compounds exhibit biological activities, including anti-cancer properties. This makes them of significant interest in medicinal chemistry.
  • Versatile Syntheses: The synthesis of 2-(4-bromophenyl)indane-1,3-dione often involves multi-step organic reactions, showcasing the complexity and creativity required in organic synthesis. Such reactions may include Friedel-Crafts acylation and cyclization processes.
  • Application in Dye Chemistry: Due to their chromophoric characteristics, indanedione derivatives like this one can serve as intermediates in dye synthesis, providing vibrant colors to textiles and inks.
  • Research Frontier: The coupling of bromophenyl moiety with indan-1,3-dione facilitates the exploration of new pharmacophores, driving advancements in drug design and development.

As a student of chemistry, understanding the multifaceted roles of compounds like 2-(4-bromophenyl)indane-1,3-dione highlights the intricate connections between organic structures and their practical applications. The exploration of such compounds fosters innovation and inspires future discoveries in the realm of science.

Synonyms
BROMINDIONE
1146-98-1
Bromophenindione
Fluidane
Haldinone
Halinone
p-Bromindione
2-(p-Bromophenyl)-1,3-indandione
1H-Indene-1,3(2H)-dione, 2-(4-bromophenyl)-
Bromindionum
Bromindiona
p-Bromphenylindandione
2-(4-Bromophenyl)-1,3-indandione
2-p-Bromophenylindandione
Bromindionum [INN-Latin]
Bromindiona [INN-Spanish]
2-(4-Bromophenyl)-1H-indene-1,3(2H)-dione
Bromindione [USAN:INN:BAN]
1,3-Indandione, 2-(p-bromophenyl)-
OQZ7BND2QN
M.G. 2555
2-(4-Bromofenil)-1,3-indandione
HL 255
NSC-759118
MG 2555
BRN 1878512
DTXSID8046244
2-(4-Bromofenil)-1,3-indandione [Italian]
BROMINDIONE [MI]
BROMINDIONE [INN]
BROMINDIONE [USAN]
DTXCID6026244
NSC 759118
Bromindionum (INN-Latin)
Bromindiona (INN-Spanish)
fluidemin
2-(4-Bromo-phenyl)-indan-1,3-dione
653-821-7
2-(4-bromophenyl)indene-1,3-dione
Fluidane;Halinone
NCGC00160590-01
CAS-1146-98-1
SR-01000078264
UNII-OQZ7BND2QN
2-(4-Bromophenyl)indan-1,3-dione
Circladin
2-(4-bromophenyl)-2,3-dihydro-1H-indene-1,3-dione
Bromindione (USAN/INN)
MLS001195122
SCHEMBL309223
CHEMBL288496
CHEBI:135274
NPUZIGSOEWMFKK-UHFFFAOYSA-N
HMS2093H17
HMS2864B20
Pharmakon1600-01505414
HY-B0917
LBC96530
2-(p-Bromophenyl)indan-1,3-dione
Tox21_111919
2-(p-Bromophenyl)-1,3-indanedione
HL-255
MFCD00087378
NSC759118
AKOS001483155
Tox21_111919_1
CCG-103151
MG-2555
1,3-Indandione, 2-(4-bromophenyl)-
NCGC00160590-03
DA-51407
Indane-1,3-dione, 2-(4-bromophenyl)-
MS-24339
SMR000554436
SY347791
SBI-0206853.P001
NS00123838
D03164
F85191
AB00823776_07
2-(4-Bromophenyl)-1H-indene-1,3(2H)-dione #
SR-01000078264-1
SR-01000078264-3
BRD-K50490982-001-08-2
Q27285793