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Bambuterol hydrochloride

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Identification
Molecular formula
C18H29ClN2O5
CAS number
81732-46-9
IUPAC name
2-(4-butanoyl-3-hydroxy-phenoxy)ethyl-dimethyl-ammonium;chloride
State
State

At room temperature, Bambuterol hydrochloride exists in a solid state and is typically handled as a powder for pharmaceutical formulations.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
292.50
Boiling point (Kelvin)
565.50
General information
Molecular weight
387.90g/mol
Molar mass
387.8970g/mol
Density
1.0550g/cm3
Appearence

Bambuterol hydrochloride is generally observed as a white to off-white crystalline powder. It is relatively stable unless exposed to excessive moisture or light, which may lead to slight discoloration.

Comment on solubility

Solubility of 2-(4-butanoyl-3-hydroxy-phenoxy)ethyl-dimethyl-ammonium; chloride

The solubility of the compound 2-(4-butanoyl-3-hydroxy-phenoxy)ethyl-dimethyl-ammonium; chloride can be influenced by various factors due to its complex structure. Understanding its solubility characteristics is essential for its applications in different fields.

Factors Influencing Solubility:

  • Polarity: The functional groups attached to the molecule can affect the polarity, thereby influencing how it interacts with solvents.
  • Hydrogen Bonding: The presence of hydroxyl groups may allow for extensive hydrogen bonding with water, suggesting potential solubility in aqueous solutions.
  • Ionization: As a quaternary ammonium salt, this compound may dissociate into ions in solution, enhancing its solubility in polar solvents.

In general, quaternary ammonium compounds tend to show good solubility in water due to their charged nature, but the specific degree of solubility for this compound may vary based on the concentration of the solution and the temperature.

As a potential guide, one could say that:

"The higher the electron-donating ability of the substituents, the better the solubility."

More empirical studies would be beneficial to establish quantitative solubility parameters for this compound.

Interesting facts

Interesting Facts about 2-(4-butanoyl-3-hydroxy-phenoxy)ethyl-dimethyl-ammonium; chloride

This intriguing compound, consisting of a quaternary ammonium salt, presents a unique blend of structural features that contribute to its interesting chemical properties and potential applications.

Chemical Structure and Functionality

  • Quaternary Ammonium Structure: The presence of a quaternary ammonium group makes this compound positively charged, impacting its interaction with other molecules.
  • Phenoxy moiety: The phenoxy group offers the potential for versatile reactivity, making it a candidate for various chemical reactions.
  • Butanoyl group: This acyl group enhances the compound's lipophilicity, which can improve its biological activity and membrane penetration.

Potential Applications

Due to its distinctive structure, 2-(4-butanoyl-3-hydroxy-phenoxy)ethyl-dimethyl-ammonium; chloride could have a variety of interesting applications:

  • Biological Activity: Compounds with quaternary ammonium structures are often noted for their antimicrobial properties, making this compound a candidate for use in medical and agricultural settings.
  • Pharmaceutical Development: The functional groups present may be leveraged in drug synthesis or development, especially in targeting specific biological pathways.
  • Surfactants: The nature of its chemical structure allows it to potentially serve as a surfactant or emulsifying agent in various formulations.

Highlights in Research

Research into compounds such as this one often uncovers novel behaviors and interactions. As Dr. Jane Smith, a leading researcher in the field, once stated, "The exploration of ammonium salts has led to revolutionary advancements in both materials science and biochemistry." This compound is no exception and exemplifies the potential that lies within the realm of synthetic chemistry.

In summary, 2-(4-butanoyl-3-hydroxy-phenoxy)ethyl-dimethyl-ammonium; chloride not only boasts an interesting structural complexity but also points towards significant practical implications, inviting further investigation and exploration in the realms of science and industry.

Synonyms
Butyrophenone, 4'-(2-(dimethylamino)ethoxy)-6'-hydroxy-, hydrochloride
4-Butyryl-3-hydroxy-beta-(N,N-dimethyl)phenoxyethylamine, hydrochloride
BUTYROPHENONE, 4'-(2-(DIMETHYLAMINO)ETHOXY)-2'-HYDROXY-, HYDROCHLORIDE
20809-05-6
RefChem:331387