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Buthiazide

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Identification
Molecular formula
C15H21NO3
CAS number
146-09-8
IUPAC name
2-(4-butoxy-3-methyl-phenyl)ethanehydroxamic acid
State
State
At room temperature, this compound is usually in a solid state, appearing as a crystalline powder.
Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
432.50
Boiling point (Kelvin)
705.65
General information
Molecular weight
285.37g/mol
Molar mass
285.3710g/mol
Density
1.1200g/cm3
Appearence

This compound typically appears as off-white to beige crystalline powder. It does not have a prominent odor and has a slightly bitter taste.

Comment on solubility

Solubility of 2-(4-butoxy-3-methyl-phenyl)ethanehydroxamic acid

The solubility of **2-(4-butoxy-3-methyl-phenyl)ethanehydroxamic acid** can be influenced by several factors, including its molecular structure and the surrounding solvent environment. As a hydroxamic acid, it possesses functional groups that can engage in various intermolecular interactions, which can significantly impact its solubility characteristics.

Factors Affecting Solubility:

  • Polarity: With its hydroxamic acid functional group, the compound exhibits potential hydrogen bonding capabilities, which can enhance solubility in polar solvents like water.
  • Substituents: The presence of the butoxy and methyl groups increases hydrophobic character, which may limit solubility in water but can improve solubility in organic solvents.
  • Temperature: Generally, an increase in temperature can result in higher solubility for many compounds, allowing better interaction of solute molecules with the solvent.

In practice, it is often observed that the phase behavior of such compounds can fluctuate between solubility in aqueous and non-aqueous environments. Thus, it is vital to assess empirical data to determine the specific solubility parameters for potential applications. Depending on the solvent system and the concentration of the compound, solubility may vary widely.

In conclusion, understanding the solubility of 2-(4-butoxy-3-methyl-phenyl)ethanehydroxamic acid requires a multifaceted approach, examining both the chemical structure and the context of its use.

Interesting facts

Interesting Facts about 2-(4-butoxy-3-methyl-phenyl)ethanehydroxamic acid

2-(4-butoxy-3-methyl-phenyl)ethanehydroxamic acid is a fascinating compound that intersects various fields of chemistry, especially in the areas of medicinal and synthetic chemistry. Here are some intriguing aspects of this compound:

  • Versatile Applications: This compound has potential applications in drug development, particularly as a hydroxamic acid derivative, which is known to possess anti-cancer properties.
  • Structure-Activity Relationship: The unique structure provides opportunities for modifying its chemical properties to enhance efficacy and reduce toxicity, making it a key candidate for synthesis studies.
  • Hydroxamic Acids: Compounds like this one, with hydroxamic acid functional groups, are notable for their ability to chelate metal ions. This property is important in various biological processes and industrial applications.
  • Researchers' Interest: Scientists are continually exploring the various reactions and pathways involving hydroxamic acids, which can lead to the discovery of new pharmacological agents.

As noted by a leading researcher in the field, "The exploration of derivatives of hydroxamic acids opens up new avenues in targeted therapy, providing a versatile tool in the fight against cancer." This statement emphasizes the importance of structural modifications in enhancing the compound's therapeutic potential.

In summary, 2-(4-butoxy-3-methyl-phenyl)ethanehydroxamic acid not only has intriguing properties on its own but also serves as a gateway to innovative research and development in medical chemistry. Its synthesis, modification, and application may yield significant contributions to the future of pharmacotherapy.

Synonyms
2-(4-Butoxy-m-tolyl)acetohydroxamic acid
2338-01-4
BRN 2656010
ACETOHYDROXAMIC ACID, 2-(4-BUTOXY-m-TOLYL)-
SCHEMBL2777075
DTXSID20946052
2-(4-Butoxy-3-methylphenyl)-N-hydroxyethanimidic acid