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Varenicline tartrate

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Identification
Molecular formula
C13H28N4O5Cl
CAS number
375815-87-5
IUPAC name
2-(4-butoxyphenoxy)-N-(2,5-diethoxyphenyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)acetamide;chloride
State
State

This compound is typically solid at room temperature. It forms a crystalline structure and is commonly available as a crystalline powder for research or pharmacological use.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.00
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.00
General information
Molecular weight
361.87g/mol
Molar mass
361.8680g/mol
Density
1.0100g/cm3
Appearence

Varenicline tartrate appears as white to off-white to slightly yellow crystalline solid.

Comment on solubility

Solubility of 2-(4-butoxyphenoxy)-N-(2,5-diethoxyphenyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)acetamide;chloride

The solubility of the compound 2-(4-butoxyphenoxy)-N-(2,5-diethoxyphenyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)acetamide;chloride presents a fascinating profile due to its complex structure and ionic nature. This compound features both hydrophobic (butoxy and diethoxy groups) and hydrophilic (pyrrolidinium) sections, influencing its solubility in various solvents.

Factors Influencing Solubility:

  • Polarity: The presence of the quaternary ammonium ion contributes to significant ionic character, suggesting that the compound is likely to be soluble in polar solvents, particularly water.
  • Hydrophobic Interactions: The butoxy and diethoxy groups may reduce solubility in non-polar solvents, as they introduce a lipophilic character that can dominate solute-solvent interactions.
  • Functional Groups: The various functional groups can engage in hydrogen bonding, further enhancing solubility in polar media.

It's noteworthy that solubility can be described as a balance between these factors, leading to the conclusion that:

"A compound's solubility characteristics can often be predicted by understanding its molecular architecture."

In practical applications, measuring the solubility in various solvents would be crucial for determining the suitability of 2-(4-butoxyphenoxy)-N-(2,5-diethoxyphenyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)acetamide;chloride for use in different chemical environments. Thus, a thorough investigation into this compound’s solubility would be an essential step in its application and development.

Interesting facts

2-(4-butoxyphenoxy)-N-(2,5-diethoxyphenyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)acetamide; chloride

This intriguing compound, often referenced in cutting-edge pharmacological research, embodies innovative approaches to drug design, particularly in the realm of neurological and psychiatric disorders. As scientists delve into the complexities of this compound, several notable aspects come to light:

  • Versatile Functional Groups: The structure showcases multiple functional groups, making it an excellent candidate for various pharmacological activities. The integration of a butoxy group and two ethoxy groups positions this compound favorably for lipid solubility, which is critical for cell membrane penetration.
  • Pyrrolidin-1-ium-1-ylethyl Moiety: This specific moiety suggests potential interactions with neurotransmitter systems, raising interest in its possible applications in treating mood disorders or neurological conditions.
  • Research Potential: The unique combination of substituents hints at a complex mechanism of action, leading researchers to explore how this compound might affect signal transduction pathways in the brain.
  • Chloride Ion Significance: The presence of the chloride ion could enhance the compound's stability and reactivity, affecting its bioavailability and overall pharmacokinetics.

Overall, the exploration of 2-(4-butoxyphenoxy)-N-(2,5-diethoxyphenyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)acetamide; chloride serves as a testament to the ingenuity of modern chemistry. As researchers continue to decipher its potential applications, this compound stands out as a promising subject for future studies, emphasizing the dynamic intersection of chemical compound design and medical therapeutic development.

Synonyms
Acetanilide, 2-(p-butoxyphenoxy)-2',5'-diethoxy-N-(2-(1-pyrrolidinyl)ethyl)-, hydrochloride
2-(p-Butoxyphenoxy)-2',5'-diethoxy-N-(2-(1-pyrrolidinyl)ethyl)acetanilide hydrochloride
27682-57-1
RefChem:315729