Skip to main content

2-(4-butylsulfanylphenyl)ethanehydroxamic acid

ADVERTISEMENT
Identification
Molecular formula
C12H17NO2S
CAS number
444731-72-0
IUPAC name
2-(4-butylsulfanylphenyl)ethanehydroxamic acid
State
State

At room temperature, 2-(4-butylsulfanylphenyl)ethanehydroxamic acid is in a solid state. The compound is generally stable under normal conditions and can be handled in a laboratory environment as a solid powder or crystalline substance.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
415.65
Boiling point (Kelvin)
688.80
General information
Molecular weight
253.35g/mol
Molar mass
253.3650g/mol
Density
1.2023g/cm3
Appearence

This compound typically appears as a white to off-white solid. It is often in crystalline form and can have a powdered appearance. Its physical state can vary depending on its purity and the specific conditions of its environment.

Comment on solubility

Solubility of 2-(4-butylsulfanylphenyl)ethanehydroxamic acid

2-(4-butylsulfanylphenyl)ethanehydroxamic acid, with its complex structure, displays a range of solubility behaviors influenced by its functional groups. Understanding its solubility is crucial when considering its applications in various chemical processes.

Factors Affecting Solubility

  • Polar and Nonpolar Regions: The compound contains both polar (-OH hydroxamic group) and nonpolar segments (the butyl group), which influences its solubility in different solvents.
  • Hydrogen Bonding: The presence of the hydroxamic acid group can participate in hydrogen bonding, enhancing solubility in polar solvents like water.
  • Temperature: Like many organic compounds, solubility can increase with temperature, although this varies based on the solvent used.
  • pH Levels: The ionization state of the hydroxamic acid function can significantly alter solubility, making it more soluble in alkaline conditions.

In summary, 2-(4-butylsulfanylphenyl)ethanehydroxamic acid exhibits a nuanced solubility profile, depending on the solvent and environmental conditions. Its behavior in aqueous solutions is likely to be more favorable due to the polar nature of the hydroxamic acid group, while nonpolar solvents may yield lower solubility. Understanding these characteristics is essential for effectively utilizing this compound in research and industrial applications.

Interesting facts

Interesting Facts about 2-(4-butylsulfanylphenyl)ethanehydroxamic Acid

2-(4-butylsulfanylphenyl)ethanehydroxamic acid is a fascinating compound known for its potential applications in medicinal chemistry and organic synthesis. Here are some intriguing aspects of this compound:

  • Novel Functional Group: This compound features a hydroxamic acid functional group, which is significant in pharmaceuticals. Hydroxamic acids can act as metal chelators and are involved in the inhibition of certain enzymes.
  • Bioactive Properties: Compounds containing a sulfanyl group (as seen in this molecule) often exhibit unique biological activities. They may be studied for their anticancer, antimicrobial, or anti-inflammatory effects.
  • Versatile Synthetic Routes: The construction of this compound opens avenues for various synthetic strategies, including coupling reactions and functionalization of aromatic rings, illustrating the versatility of organic chemistry.
  • Environmental Applications: Due to the presence of the sulfanyl moiety, there may be potential in environmental chemistry, such as in the degradation of pollutants or in remediation strategies.
  • Structure-Activity Relationship Studies: The compound serves as an excellent candidate for SAR studies, allowing scientists to modify different parts of the molecule to understand their effects on biological activity.

In summary, 2-(4-butylsulfanylphenyl)ethanehydroxamic acid stands out not only for its structural complexity but also for its promising applications in science and medicine. As research progresses, this compound could contribute significantly to advancements in therapeutic agents and chemical methodologies.

Synonyms
2385-93-5
BRN 2646849
ACETOHYDROXAMIC ACID, 2-(p-BUTYLTHIO)PHENYL-
2-(p-Butylthio)phenylacetohydroxamic acid
DTXSID20178553
DTXCID80101044