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Folinic Acid

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Identification
Molecular formula
C20H23N7O7
CAS number
58-05-9
IUPAC name
2-[[4-carboxy-4-[2-[hydroxy-[2,3,4-trihydroxy-5-(2,4,8-trioxo-1H-pyrimido[4,5-b]quinolin-10-yl)pentoxy]phosphoryl]oxypropanoylamino]butanoyl]amino]pentanedioic acid
State
State

At room temperature, folinic acid is typically found as a solid.

Melting point (Celsius)
237.00
Melting point (Kelvin)
510.15
Boiling point (Celsius)
542.00
Boiling point (Kelvin)
815.15
General information
Molecular weight
474.45g/mol
Molar mass
474.4460g/mol
Density
2.2100g/cm3
Appearence

Folinic acid typically appears as a pale yellow or yellow crystalline powder.

Comment on solubility

Solubility of 2-[[4-carboxy-4-[2-[hydroxy-[2,3,4-trihydroxy-5-(2,4,8-trioxo-1H-pyrimido[4,5-b]quinolin-10-yl)pentoxy]phosphoryl]oxypropanoylamino]butanoyl]amino]pentanedioic acid

The solubility of 2-[[4-carboxy-4-[2-[hydroxy-[2,3,4-trihydroxy-5-(2,4,8-trioxo-1H-pyrimido[4,5-b]quinolin-10-yl)pentoxy]phosphoryl]oxypropanoylamino]butanoyl]amino]pentanedioic acid (C20H23N7O7) is a topic of considerable interest due to its complex structure and multiple functional groups. The solubility characteristics can be summarized as follows:

  • Hydrophilicity: This compound contains multiple hydroxyl (-OH) groups and a carboxylic acid (-COOH) moiety, which enhance its ability to interact with water molecules.
  • Polarity: The nitrogen and oxygen atoms contribute to a higher polarity that often leads to increased solubility in polar solvents like water.
  • Effect of pH: The solubility may vary significantly with pH levels due to the ionizable groups, creating different ionic forms that can affect solubility.
  • Precipitation: In certain conditions, particularly at low pH or high concentration, aggregation or precipitation of the compound may occur due to intermolecular interactions.

In summary, while the compound is expected to be soluble in polar solvents, factors such as concentration, temperature, and pH will play a critical role in its effective solubility. As noted, “Understanding the solubility behavior of complex compounds is crucial for their application in biological systems and pharmaceuticals.”


Interesting facts

Interesting Facts about 2-[[4-carboxy-4-[2-[hydroxy-[2,3,4-trihydroxy-5-(2,4,8-trioxo-1H-pyrimido[4,5-b]quinolin-10-yl)pentoxy]phosphoryl]oxypropanoylamino]butanoyl]amino]pentanedioic Acid

This compound is a fascinating example of how chemistry can intertwine intricate molecular structures with significant biological implications. As a derivative of quinoline, this compound is of particular interest in medicinal chemistry due to its potential as a pharmaceutical agent. Here are some compelling characteristics:

  • Complex Structure: The molecule features multiple functional groups, including carboxylic acids, hydroxyl groups, and a quinoline moiety, contributing to its diverse reactivity and biological activity.
  • Biological Relevance: Compounds of this class are often studied for their roles in anti-cancer and anti-inflammatory activities. Their multifaceted interactions with biological targets make them compelling candidates for drug development.
  • Chemistry of Functionality: The presence of multiple hydroxyl groups in this structure enhances its potential for hydrogen bonding, influencing solubility and bioavailability.
  • Phosphoryl Group Insight: The phosphoryl group plays a critical role in biochemical processes, including energy transfer and signaling pathways, highlighting the compound's potential importance in cellular functions.
  • Ecological Impact: Due to their complexity, these compounds could hold significance in the development of environmentally friendly pesticides or growth regulators in agriculture.

In summary, the exploration of 2-[[4-carboxy-4-[2-[hydroxy-[2,3,4-trihydroxy-5-(2,4,8-trioxo-1H-pyrimido[4,5-b]quinolin-10-yl)pentoxy]phosphoryl]oxypropanoylamino]butanoyl]amino]pentanedioic acid leads to exciting possibilities in both medicinal and ecological fields. As chemistry continues to evolve, compounds like this could inspire future breakthroughs in health and sustainability.

Synonyms
SCHEMBL16018850