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Clonixin

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Identification
Molecular formula
C9H8ClNO3
CAS number
17726-19-5
IUPAC name
2-[(4-chlorobenzoyl)amino]acetic acid
State
State

At room temperature, Clonixin is a solid.

Melting point (Celsius)
219.00
Melting point (Kelvin)
492.15
Boiling point (Celsius)
365.10
Boiling point (Kelvin)
638.25
General information
Molecular weight
213.63g/mol
Molar mass
213.6260g/mol
Density
1.4600g/cm3
Appearence

Clonixin is typically found as a white to slightly off-white crystalline powder.

Comment on solubility

Solubility of 2-[(4-chlorobenzoyl)amino]acetic acid

The solubility of 2-[(4-chlorobenzoyl)amino]acetic acid, also known as a derivative of amino acids, is influenced by several key factors. Understanding its solubility can provide insights into its behavior in various environments:

  • Polarity: The polar nature of the compound due to the presence of both amino and carboxylic acid functional groups generally enhances its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability of this compound to form hydrogen bonds with water molecules increases its potential solubility.
  • pH Dependence: The solubility can vary significantly with pH, as the ionization of the carboxylic group in acidic or basic conditions can affect the overall solute-solvent interactions.
  • Temperature Effects: Like many compounds, solubility often increases with a rise in temperature, allowing for more effective dissolution.

In practical applications, it is quoted that "solubility is a gateway to chemical reactivity." Therefore, comprehending how 2-[(4-chlorobenzoyl)amino]acetic acid interacts with solvents aids in its utilization in pharmaceuticals and other industries.

In summary, while this compound exhibits promising solubility characteristics, further studies may be needed to elucidate the precise solubility parameters under varying conditions.

Interesting facts

Interesting Facts About 2-[(4-chlorobenzoyl)amino]acetic acid

2-[(4-chlorobenzoyl)amino]acetic acid is a fascinating compound that belongs to the class of amino acids and synthetic pharmaceuticals. Below are some intriguing aspects that highlight its significance in the field of chemistry and pharmacology:

  • Dual Functionality: This compound serves as both an amino acid due to the presence of the amino group and as a carboxylic acid, indicating its potential use in various biological systems.
  • Chlorobenzoyl Substitution: The presence of the 4-chlorobenzoyl group enhances its lipophilicity, allowing this compound to interact effectively with biological membranes.
  • Medicinal Applications: It has garnered attention for its potential role in designing therapeutic agents, particularly in anti-inflammatory and analgesic drugs.
  • Research Insights: Studies have shown that compounds with similar structures can exhibit a range of pharmacological activities, from acting as enzyme inhibitors to modulating receptor functions.
  • Environmental Considerations: The chlorine atom in the structure may impact the compound's environmental behavior, raising questions about its persistence and potential effects on ecosystems.

Considering the ongoing research and development in medicinal chemistry, 2-[(4-chlorobenzoyl)amino]acetic acid stands out as a compound with significant potential.
As the field continues to evolve, understanding such compounds could pave the way for innovative treatments and therapeutic solutions.

Synonyms
13450-77-6
4-Chlorohippuric acid
p-Chlorohippuric acid
Glycine, N-(4-chlorobenzoyl)-
p-Chlorobenzoylglycine
4-Chlorobenzoylglycine
N-(p-Chlorobenzoyl)glycine
HIPPURIC ACID, p-CHLORO-
N-(4-Chlorobenzoyl)glycine
92HJ692NVA
DTXSID40158756
DTXCID7081247
2-(4-Chlorobenzamido)acetic acid
2-[(4-chlorobenzoyl)amino]acetic acid
(4-Chloro-benzoylamino)-acetic acid
MFCD00020447
2-[(4-chlorophenyl)formamido]acetic acid
CHEMBL462
2-[(4-chlorophenyl)carbonylamino]acetic acid
[(4-chlorophenyl)formamido]acetic acid
BRN 1110511
UNII-92HJ692NVA
AI3-30805
Glycine,N-(4-chlorobenzoyl)-
2-(4-Chlorobenzamido)aceticacid
4-Chlorobenzoylglycine; N-(4-Chlorobenzoyl)glycine; N-(p-Chlorobenzoyl)glycine; Ro 11-1903; p-Chlorobenzoylglycine; p-Chlorohippuric Acid
Moclobemide metabolite M9
Cambridge id 5190259
Oprea1_302425
Oprea1_822134
3-09-00-01364 (Beilstein Handbook Reference)
SCHEMBL4002486
COYZIYOEXGRBHQ-UHFFFAOYSA-N
ALBB-033219
NAA45077
BDBM50016616
N-[(4-chlorophenyl)carbonyl]glycine
SBB004563
STK036747
AKOS000114598
PITOLISANT METABOLITE BP1.10556
ST055065
BP1.10556
CS-0157556
EN300-00184
3E-929
C72366
SR-01000412838
SR-01000412838-1
Q27271504
Z56840113
F0345-3965