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Lidocaine

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Identification
Molecular formula
C14H22ClN3O2
CAS number
137-58-6
IUPAC name
2-(4-chlorophenoxy)-N,N-bis[2-(diethylamino)ethyl]acetamide
State
State
Lidocaine is a solid at room temperature, generally found as a crystalline powder.
Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.80
General information
Molecular weight
270.80g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence
Lidocaine typically appears as a white crystalline solid. It is known to be odorless and usually occurs in the form of a powder.
Comment on solubility

Solubility of 2-(4-chlorophenoxy)-N,N-bis[2-(diethylamino)ethyl]acetamide

Understanding the solubility of 2-(4-chlorophenoxy)-N,N-bis[2-(diethylamino)ethyl]acetamide is crucial for its applications in various chemical and pharmaceutical processes. This compound exhibits interesting solubility characteristics that can be summarized as follows:

  • Solvent Compatibility: Generally soluble in polar organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO).
  • Water Solubility: Limited solubility in water. This may affect its bioavailability and efficacy in certain applications.
  • Temperature Dependence: Its solubility can be significantly influenced by temperature; increased temperatures often enhance solubility.
  • pH Influence: The solubility may vary with changes in pH, making it important to consider the solution's acidity or basicity for optimal dissolution.

As a point of reference, it's noted that "solubility is not just about how much substance dissolves, but how well it can interact with the solvent environment." This reinforces the idea that the chemical structure—characterized by both its hydrophobic and polar segments—plays a key role in its solubility profile. Consequently, a thorough understanding of these factors is essential for anyone working with this compound.

Interesting facts

Interesting Facts about 2-(4-chlorophenoxy)-N,N-bis[2-(diethylamino)ethyl]acetamide

2-(4-chlorophenoxy)-N,N-bis[2-(diethylamino)ethyl]acetamide is a fascinating compound with a variety of applications in the field of pharmacology and organic chemistry. Here are some captivating insights:

  • Pharmacological Relevance: This compound is known for its potential use as a therapeutic agent. Its structure suggests that it may interact with various biological pathways, making it a candidate for drug development.
  • Chlorophenyl Influence: The presence of the 4-chlorophenoxy group is significant. Chlorinated phenols often enhance the biological activity of compounds due to their ability to interact with cellular targets and increase lipophilicity.
  • Diethylamino Moiety: The diethylamino groups in the molecule contribute to its unique properties. The nitrogen atoms play a crucial role in the compound's basicity and ability to form hydrogen bonds, which can affect its solubility and interaction with biological receptors.
  • Structure-Activity Relationship (SAR): Understanding the SAR of this compound can unravel how its molecular modifications influence its biological effects. This is essential in the design of more effective drugs with fewer side effects.
  • Studies and Research: Ongoing research into this compound may uncover its mechanisms of action, providing insight into how it may be utilized in therapeutic contexts, particularly in treating neurological disorders or as an anesthetic.
  • Future Prospects: The potential for this compound to serve as a scaffolding structure for further derivatization opens exciting possibilities in medicinal chemistry.

Overall, 2-(4-chlorophenoxy)-N,N-bis[2-(diethylamino)ethyl]acetamide exemplifies the intricate relationship between chemical structure and biological activity, making it an important subject of study for scientists and researchers alike.

Synonyms
1170-51-0
ACETAMIDE, N,N-(BIS(2-(DIETHYLAMINO)ETHYL))-2-(4-CHLOROPHENOXY)-
NP 1080
BRN 2013325
Acetamide, 2-(4-chlorophenoxy)-N,N-bis(2-(diethylamino)ethyl)-
Acetamide, 2-(P-chlorophenoxy)-N,N-bis(2-(diethylamino)ethyl)-
DTXSID40151661
N,N-(Bis(2-(diethylamino)ethyl))-2-(4-chlorophenoxy)acetamide
DTXCID8074152
Acetamide, 2-(4-chlorophenoxy)-N,N-bis(2-(diethylamino)ethyl)-(9CI)
Acetamide, 2-(P-chlorophenoxy)-N,N-bis(2-(diethylamino)ethyl)-(8CI)
2-(4-chlorophenoxy)-N,N-bis[2-(diethylamino)ethyl]acetamide