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2-(4-chlorophenyl)-1-cyano-guanidine

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Identification
Molecular formula
C8H7ClN4
CAS number
38465-60-0
IUPAC name
2-(4-chlorophenyl)-1-cyano-guanidine
State
State

At room temperature, the compound is in a solid state, specifically as crystalline powder.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.00
Boiling point (Celsius)
379.00
Boiling point (Kelvin)
652.00
General information
Molecular weight
193.62g/mol
Molar mass
193.6200g/mol
Density
1.3880g/cm3
Appearence

The compound appears as a white to off-white crystalline solid. It may have a characteristic smell depending on the purity and specific preparation method.

Comment on solubility

Solubility of 2-(4-chlorophenyl)-1-cyano-guanidine

The solubility of 2-(4-chlorophenyl)-1-cyano-guanidine can be influenced by several factors, including temperature, pH, and the presence of solvents. This compound exhibits unique characteristics that may affect its solubility:

  • Solvent Interactions: It is important to note that 2-(4-chlorophenyl)-1-cyano-guanidine may be more soluble in polar aprotic solvents compared to nonpolar solvents. Solvents such as DMSO or methanol may facilitate better dissolution due to favorable interactions.
  • Temperature Effects: Generally, an increase in temperature can lead to an improvement in solubility for many organic compounds. Thus, warming the solution might help in achieving a higher concentration.
  • pH Dependency: The solubility can also be pH-dependent. Adjusting the pH may enhance the ionization of certain functional groups, thus improving solubility in aqueous media.

In practical terms, if you're working with 2-(4-chlorophenyl)-1-cyano-guanidine, consider the factors listed as they play a crucial role in its solubility behavior. Understanding these dynamics can help in effectively utilizing the compound in various applications.

Interesting facts

Interesting Facts about 2-(4-chlorophenyl)-1-cyano-guanidine

2-(4-chlorophenyl)-1-cyano-guanidine, commonly referred to as a derivative of guanidine, is a fascinating compound that has garnered attention for its diverse applications. Here are some intriguing aspects of this compound:

  • Pharmaceutical Applications: This compound is often studied for its potential use in pharmaceuticals, particularly in the synthesis of various medicinal agents.
  • Biological Importance: As a guanidine derivative, it can mimic amino acids, which makes it pivotal in exploring mechanisms of action of protein functions.
  • Research Potential: Scientists have shown interest in its nitrile functional group, which may give rise to different reactivity patterns that could be useful in organic synthesis.
  • Environmental Considerations: With growing environmental awareness, researchers are investigating the degradation pathways of compounds like this one to understand their impact on ecosystems.

Due to the presence of the 4-chlorophenyl group, this compound can exhibit unique electronic properties that can influence its reactivity and interaction with other substances. The cyano group adds a layer of versatility, enhancing its appeal in various synthesis routes. As a result, ongoing research continues to reveal its multifaceted roles in science.

Quote from the Literature: "Guanidine derivatives are a subtle yet potent class of compounds that illuminate the delicate balance of structure and function in biology."

This compound exemplifies how small changes in molecular structure can lead to significant variations in properties and applications, making it a prime subject for further study in both chemistry and related scientific fields.

Synonyms
1482-62-8
1-(4-Chlorophenyl)-3-cyanoguanidine
Guanidine, N-(4-chlorophenyl)-N'-cyano-
N-(4-Chlorophenyl)-N'-cyanoguanidine
1-(p-Chlorophenyl)-3-cyanoguanidine
N-(p-Chlorophenyl)dicyandiamide
1-(p-Chlorophenyl)dicyanodiamide
1-(p-Chlorophenyl)-3-cyanoguanidin
NSC 74463
GUANIDINE, 1-(p-CHLOROPHENYL)-3-CYANO-
4-Chlor-phenyl-dicyandiamin
EINECS 216-043-5
NSC-74463
4-Chlor-phenyl-dicyandiamin [German]
BRN 2213286
UNII-X27G052788
1-Cyano-3-(4-chlorophenyl)guanidine
X27G052788
DTXSID10163933
4-12-00-01197 (Beilstein Handbook Reference)
PROGUANIL HYDROCHLORIDE IMPURITY E [EP IMPURITY]
PROGUANIL HYDROCHLORIDE IMPURITY E (EP IMPURITY)
DTXCID0086424
Guanidine, N-(4-chlorophenyl)-N'-cyano-(9CI)
216-043-5
p-Chlorophenyldicyandiamide
p-chlorophenyl-cyanoguanidine
p-Chlorophenylcyanoguanidine
NSC74463
2-(4-chlorophenyl)-1-cyanoguanidine
1-(4-chlorophenyl)-3-cyano-guanidine
3-(4-chlorophenyl)-1-cyanoguanidine
MFCD01724336
Maybridge1_004360
WLN: NCMYUM&MR DG
NCIStruc1_000255
NCIStruc2_000003
SCHEMBL1108190
CHEMBL1329926
SCHEMBL16333454
HMS553O06
N-p-chlorophenyl-N'-cyanoguanidine
BCP28543
NCI74463
CCG-36252
NCGC00013817
STL140821
1-(4-chlorophenyl)-2-cyanoguanidine
AKOS005720992
N-(4-Chlorophenyl)-N?-cyanoguanidine
N-(4-chlorophenyl)-N''-cyanoguanidine
NCGC00013817-02
NCGC00096927-01
AS-17423
NCI60_041629
CS-0324317
NS00021674
D86422
AL-398/25017011
Q27293403
N-(4-Chlorophenyl)-N inverted exclamation marka-cyanoguanidine