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Cloperastine

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Identification
Molecular formula
C21H23ClN2
CAS number
3703-76-2
IUPAC name
2-[(4-chlorophenyl)-(1-methyl-4-piperidylidene)methyl]pyridine
State
State
At room temperature, Cloperastine is typically found in a solid state as it is a crystalline compound.
Melting point (Celsius)
131.00
Melting point (Kelvin)
404.15
Boiling point (Celsius)
307.30
Boiling point (Kelvin)
580.45
General information
Molecular weight
348.88g/mol
Molar mass
348.8600g/mol
Density
1.1500g/cm3
Appearence
Cloperastine appears as a white to off-white crystalline powder. It may be slightly yellowish and is typically odorless or may have a faint characteristic odor.
Comment on solubility

Solubility of 2-[(4-chlorophenyl)-(1-methyl-4-piperidylidene)methyl]pyridine

The solubility of 2-[(4-chlorophenyl)-(1-methyl-4-piperidylidene)methyl]pyridine presents interesting characteristics owing to its structural complexity. This compound is likely to exhibit a varied solubility in different solvents, influenced by the polarity and functional groups present in its structure.

Key Factors Affecting Solubility:

  • Polarity: The presence of both aromatic and polar functional groups may lead to solubility in polar solvents like water, as well as non-polar solvents.
  • Hydrogen Bonding: Potential for hydrogen bonding increases solubility in certain protic solvents.
  • Temperature: Like most organic compounds, its solubility may increase with temperature.
  • pH Levels: The basicity or acidity of the solution can significantly influence its solubility profile.

As a general guideline:

  • Compounds with significant hydrophobic regions tend to be less soluble in water.
  • Conversely, compounds that can participate in hydrogen bonding often show higher solubility in water.

In conclusion, while predicting the exact solubility without experimental data can be challenging, the dual nature of the compound's structure may lead to solubilization in a range of environments. For optimized applications, empirical testing in various solvents is recommended.

Interesting facts

Interesting Facts about 2-[(4-chlorophenyl)-(1-methyl-4-piperidylidene)methyl]pyridine

The compound 2-[(4-chlorophenyl)-(1-methyl-4-piperidylidene)methyl]pyridine is an intriguing molecule in the field of medicinal chemistry. Below are some engaging facts about this compound:

  • Structural Complexity: This compound features a unique hybrid structure, combining a pyridine ring with a piperidine moiety. Such structural intricacies often contribute to varied biological activities.
  • Pharmacological Potential: The presence of the piperidine group suggests potential applications in pharmacology. Compounds with similar structures are frequently investigated for their ability to interact with neurotransmitter systems.
  • Chirality: The presence of chiral centers within the piperidine ring means that stereochemistry plays a critical role in the compound's activity. The specific isomer may exhibit different pharmacological properties, underscoring the importance of stereochemistry in drug design.
  • Antitumor Activity: Research indicates that compounds of this type may exhibit antitumor properties, making them candidates for further investigation in cancer therapy.
  • Targeted Research: Scientists are focusing on compounds with similar frameworks to explore their interactions with various targets including but not limited to serotonin receptors, which can influence mood and anxiety.

As researchers continue to explore the potential of 2-[(4-chlorophenyl)-(1-methyl-4-piperidylidene)methyl]pyridine, it highlights the vibrant intersection of chemistry and medicine, reminding us that every compound has its own story waiting to be discovered.

Synonyms
Cycliramine
Cycliraminum
Cycliramin
Cycliramina
Cycliramine [INN]
47128-12-1
UNII-N61YTN00CK
N61YTN00CK
cicliramina
2-(4-Chlor-alpha-(1-methyl-4-piperidyliden)benzyl)pyridin
4-(p-Chloto-slpha-(2-pyridyl)benzylidene)-1-methylpiperidine
4-(P-CHLORO-.ALPHA.-2-PYRIDYLBENZYLIDENE)-1-METHYLPIPERIDINE
PYRIDINE, 2-((4-CHLOROPHENYL)(1-METHYL-4-PIPERIDINYLIDENE)METHYL)-
4-(P-CHLORO-ALPHA-2-PYRIDYLBENZYLIDENE)-1-METHYLPIPERIDINE
2-[(4-chlorophenyl)-(1-methylpiperidin-4-ylidene)methyl]pyridine
SCHEMBL2109915
CHEMBL1618128
DTXSID50963752
2-[(4-CHLOROPHENYL)-(1-METHYL-4-PIPERIDYLIDENE)METHYL]PYRIDINE
NCGC00246866-01
Q27284599
2-[(4-CHLOROPHENYL)(1-METHYLPIPERIDIN-4-YLIDENE)METHYL]PYRIDINE