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Clomipramine

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Identification
Molecular formula
C19H23ClN2
CAS number
303-49-1
IUPAC name
2-(4-chlorophenyl)-1,3-dimethyl-imidazolidine
State
State

At room temperature, clomipramine exists as a solid.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
454.40
Boiling point (Kelvin)
727.55
General information
Molecular weight
314.86g/mol
Molar mass
314.8260g/mol
Density
1.2710g/cm3
Appearence

Clomipramine is a white to off-white crystalline powder. It is sensitive to light, and prolonged exposure to light may cause a slight yellowing of the substance.

Comment on solubility

Solubility of 2-(4-chlorophenyl)-1,3-dimethyl-imidazolidine

The solubility of 2-(4-chlorophenyl)-1,3-dimethyl-imidazolidine is an interesting aspect that can be influenced by several factors. This compound exhibits moderate solubility, primarily due to its molecular structure, which balances polar and non-polar characteristics.

Factors Influencing Solubility:

  • Polarity: The presence of the 4-chlorophenyl group enhances the compound's ability to interact with polar solvents.
  • Molecular Weight: With an increased molecular weight, the solubility in non-polar solvents tends to decrease.
  • Hydrogen Bonding: The potential for hydrogen bonds with water molecules increases solubility in aqueous environments.

Furthermore, it is often observed that solubility can be estimated through the following:

  • Temperature: Typically, increased temperature can lead to higher solubility for many organic compounds.
  • pH of the Solution: As the pH changes, the ionization state of the compound may alter, affecting solubility in water.

In summary, while 2-(4-chlorophenyl)-1,3-dimethyl-imidazolidine is not highly soluble in every solvent, its behavior in various environments can still be tailored through adjustments in conditions. As such, understanding its solubility can provide insightful implications for its applications in chemical processes.

Interesting facts

Exploring 2-(4-chlorophenyl)-1,3-dimethyl-imidazolidine

2-(4-chlorophenyl)-1,3-dimethyl-imidazolidine is a fascinating compound that belongs to the imidazolidine family. Its unique structure lends itself to a variety of interesting properties and potential applications in several fields.

Key Features:

  • Structural Diversity: The compound features a five-membered imidazolidine ring, which contributes to its cyclic stability and chemical reactivity.
  • Substituent Effects: The presence of the 4-chlorophenyl group adds significant electronic influence, enhancing the compound's physicochemical behavior, including reactivity and stability.
  • Biological Potential: Compounds with similar structures have been studied for their potential pharmacological activities. There is ongoing research into their uses in medicinal chemistry, particularly in drug design for treating various diseases.

Furthermore, imidazolidines are known for their role in the development of chiral catalysts, which are crucial in asymmetric synthesis. This positions 2-(4-chlorophenyl)-1,3-dimethyl-imidazolidine as a compound of interest in synthetic organic chemistry.

Applications and Uses:

  • Pharmaceuticals: Investigated for potential therapeutic roles, particularly in cancer treatment and as antimicrobial agents.
  • Catalysis: May serve as a platform for catalyzing various reactions due to its nitrogen-containing ring structure.
  • Material Sciences: Its derivatives could be explored in the development of novel materials, such as polymers or coatings.

Overall, 2-(4-chlorophenyl)-1,3-dimethyl-imidazolidine exemplifies the interplay between structure and function in chemical compounds, underscoring the importance of nitrogens in cyclic frameworks. As researchers continue to explore such compounds, we can expect to uncover more about their hidden potential and broaden their applications in science.

Synonyms
23281-56-3
IMIDAZOLIDINE, 2-(p-CHLOROPHENYL)-1,3-DIMETHYL-
DTXSID90177851
RefChem:1087229
DTXCID50100342
2-(p-Chlorophenyl)-1,3-dimethylimidazolidine
BRN 0957957
Imidazolidine, 2-(4-chlorophenyl)-1,3-dimethyl-
WEAVUIXCKWTMNE-UHFFFAOYSA-N
2-(4-Chlorophenyl)-1,3-dimethylimidazolidine #