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Bupivacaine

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Identification
Molecular formula
C18H28ClN3O2
CAS number
38396-39-3
IUPAC name
2-(4-chlorophenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile
State
State

Bupivacaine is typically encountered as its hydrochloride salt form at room temperature, which gives it a solid, crystalline appearance.

Melting point (Celsius)
107.50
Melting point (Kelvin)
380.65
Boiling point (Celsius)
372.40
Boiling point (Kelvin)
645.55
General information
Molecular weight
288.82g/mol
Molar mass
288.8230g/mol
Density
1.0223g/cm3
Appearence

Bupivacaine hydrochloride appears as a white crystalline powder that is odorless. It is commonly observed in the form of its hydrochloride salt for medical and pharmaceutical uses.

Comment on solubility

Solubility of 2-(4-chlorophenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile

2-(4-chlorophenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile is a compound whose solubility characteristics are worth exploring. Understanding its solubility can provide insights into its chemical behavior and its potential applications in various fields. Here are some key points regarding its solubility:

  • Polar vs. Non-Polar Solvents: The presence of a dimethylamino group suggests that this compound may exhibit some degree of solubility in polar solvents due to the availability of lone pair electrons for hydrogen bonding.
  • Overall Solubility: Compounds with multiple functional groups, such as the chloro and nitrile groups, typically show diverse solubility patterns based on their interaction with different solvents.
  • Temperature Dependence: Like many organic compounds, solubility may increase with temperature. This is an important consideration in applications involving different thermal conditions.
  • pH Sensitivity: The behavior of the compound in varying pH levels can also significantly affect its solubility properties, especially due to the presence of the basic amino group.

In conclusion, while the precise solubility of 2-(4-chlorophenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile may require experimental determination for specific solvent systems, its identifiable functional groups suggest a complex solubility profile influenced by solvent polarity, temperature, and pH. This complexity underlines the importance of assessing solubility under controlled conditions for accurate applications and research.

Interesting facts

Interesting Facts about 2-(4-Chlorophenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile

This compound, with its complex structure, is noteworthy for a number of reasons, especially within the fields of organic chemistry and pharmacology.

Key Characteristics:

  • Diversity of Functionality: The presence of a nitrile group and an amino moiety makes this compound a candidate for diverse chemical reactions, potentially leading to various derivatives.
  • Biological Relevance: It may exhibit properties that are significant in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways.
  • Regioselectivity: The unique arrangement of the phenyl and amino groups influences the regioselectivity of reactions involving this compound, making it a valuable study subject.

Potential Applications:

  • Pharmacological research into neuromodulators and their mechanisms of action.
  • Synthesis of complex organic molecules that can serve as intermediates in drug development.
  • Analytical applications in understanding the behavior of compounds under various conditions.

As a compound representing the intersection of synthetic organic chemistry and biological activity, 2-(4-chlorophenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile exemplifies the sophisticated relationships that exist between structure and function in chemical compounds. As chemists delve into its properties and reactions, who knows what new discoveries await in its exploration?

Synonyms
BRN 2124100
2-(p-Chlorophenyl)-4-(dimethylamino)-2-isopropylbutyronitrile
14780-15-5
BUTYRONITRILE, 2-(p-CHLOROPHENYL)-4-(DIMETHYLAMINO)-2-ISOPROPYL-
DTXSID90933217
2-(4-chlorophenyl)-2-[2-(dimethylamino)ethyl]-3-methylbutanenitrile