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Fenoprofen

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Identification
Molecular formula
C15H15ClO2
CAS number
[31879-05-7]
IUPAC name
2-(4-chlorophenyl)-3-methyl-butanoic acid
State
State

At room temperature, fenoprofen is in a solid state as a crystalline powder.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.00
Boiling point (Celsius)
398.00
Boiling point (Kelvin)
671.00
General information
Molecular weight
242.72g/mol
Molar mass
242.7160g/mol
Density
1.0900g/cm3
Appearence

Fenoprofen appears as a white crystalline powder. It is typically odorless and is used in the form of its calcium salt for pharmaceutical preparations.

Comment on solubility

Solubility of 2-(4-chlorophenyl)-3-methyl-butanoic acid

The solubility of 2-(4-chlorophenyl)-3-methyl-butanoic acid in various solvents is an important aspect to consider for its applications and behavior in chemical processes. Understanding its solubility can provide insights into its uses in pharmaceuticals and organic synthesis.

Key points regarding the solubility of this compound include:

  • Polar Solvents: This compound typically shows better solubility in polar solvents such as water and alcohols, due to the presence of the carboxylic acid functional group which can engage in hydrogen bonding.
  • Non-Polar Solvents: In contrast, it is less soluble in non-polar solvents like hexane or toluene, where interactions are primarily based on van der Waals forces.
  • Temperature Effects: Like many organic acids, an increase in temperature may enhance its solubility in various solvents, allowing for more effective dissolution.
  • pH Influence: The solubility can be significantly affected by the pH of the solution; the deprotonated form of the acid may increase solubility in alkaline conditions.

Overall, the solubility behavior of 2-(4-chlorophenyl)-3-methyl-butanoic acid is influenced by a myriad of factors. Understanding these aspects is crucial for its effective application in chemical research and industry.

Interesting facts

Interesting Facts about 2-(4-chlorophenyl)-3-methyl-butanoic acid

2-(4-chlorophenyl)-3-methyl-butanoic acid is a fascinating compound that falls under the category of carboxylic acids. Here are some interesting insights:

  • Bioactivity: This compound has garnered attention in the field of pharmaceuticals due to its potential bioactive properties. Its structure suggests that it could have applications in developing new therapeutic agents.
  • Analytical Chemistry: The presence of chlorine in the aromatic ring makes this compound a subject of interest for analytical methods. Techniques such as High-Performance Liquid Chromatography (HPLC) can be employed to analyze its purity and concentration.
  • Structure-Activity Relationship (SAR): Examining the structure of 2-(4-chlorophenyl)-3-methyl-butanoic acid allows researchers to explore how modifications at various positions affect its activity. This is crucial in drug design and optimization.
  • Environmental Considerations: Like many organic compounds, chlorinated compounds could pose environmental risks. Investigating their degradation pathways is essential for understanding their impact on ecosystems.
  • Research Potential: Ongoing studies could further reveal the medicinal properties and viability of utilizing this compound in different chemical processes or biological systems, making it a promising candidate for future research.

As a chemist or student, understanding the implications and applications of compounds like 2-(4-chlorophenyl)-3-methyl-butanoic acid not only deepens your knowledge of organic chemistry but also highlights the importance of chemical derivatives in advanced research areas.

Synonyms
2012-74-0
2-(4-Chlorophenyl)-3-methylbutanoic acid
2-(4-Chlorophenyl)-3-methylbutyric acid
2-(p-Chlorophenyl)-3-methylbutyric acid
alpha-Isopropyl-p-chlorophenylacetic acid
EINECS 217-934-1
CHEBI:39345
Benzeneacetic acid, 4-chloro-.alpha.-(1-methylethyl)-
BUTYRIC ACID, 2-(p-CHLOROPHENYL)-3-METHYL-
Benzeneacetic acid, 4-chloro-alpha-(1-methylethyl)-
DTXSID00883537
DTXCID60893793
217-934-1
alpha-isopropyl-4-chlorophenylacetic acid
2-(4-Chloro-phenyl)-3-methyl-butyric acid
(RS)-Fenvaleric acid
Benzeneacetic acid, 4-chloro-a-(1-methylethyl)-
CHEMBL593203
.alpha.-(p-Chlorophenyl)isovaleric acid
2-(4-Chloro-phenyl)-3-methylbutyric acid
Fenvalerate (free acid)
(S)-2-(4-CHLORO-PHENYL)-3-METHYL-BUTYRIC ACID
MFCD04112625
MFCD11858304
esfenvalerate TP2
(+/-)-2-(4-Chlorophenyl)isovaleric acid; (+/-)-2-(p-Chlorophenyl)-3-methylbutyric acid; (+/-)-Fenvaleric acid
MFCD00037763
2-(p-chlorophenyl)-3-methyl-butyric acid
Enamine_004948
SCHEMBL68169
2-(4-chlorophenyl)isovaleric acid
HMS1408A20
isopropyl(4-chlorophenyl)acetic acid
BDBM50305939
AKOS001063747
AKOS016843430
SB35162
SB37640
SB38063
IDI1_007535
NCGC00329284-01
2-(4-chlorophenyl)3-methyl butyric acid
2-isopropyl-2-p-chlorophenyl-acetic acid
AS-16160
SY025357
SY025440
2-(4-chlorophenyl)-3-methyl-butyric acid
2-(p-Chlorophenyl)-3-methyl butyric acid
DB-045102
2-(4-Chlorophenyl)-3-methylbutanoic acid #
C2741
CS-0015834
NS00046315
EN300-04178
rac-2-(4-chlorophenyl)-3-methylbutanoic acid
2-(4-Chlorophenyl)-3-methylbutyric acid, 96%
AB00633355-03
(2RS)-2-(4-chlorophenyl)-3-methylbutanoic acid
4-chloro-alpha-(1-methyl-ethyl)benzeneacetic acid
SR-01000039639
SR-01000039639-1
Q27119827
Z56887655
()-2-(4-Chlorophenyl)isovaleric acid; ()-2-(p-Chlorophenyl)-3-methylbutyric acid; ()-Fenvaleric acid