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Clomiphene

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Identification
Molecular formula
C26H28ClNO
CAS number
911-45-5
IUPAC name
2-(4-chlorophenyl)-3-phenyl-prop-2-enenitrile
State
State

Clomiphene is a solid at room temperature. It is generally stored in airtight containers to protect it from moisture and light.

Melting point (Celsius)
116.50
Melting point (Kelvin)
389.60
Boiling point (Celsius)
563.30
Boiling point (Kelvin)
836.50
General information
Molecular weight
405.97g/mol
Molar mass
405.9660g/mol
Density
1.1250g/cm3
Appearence

Clomiphene is typically a white to pale yellow, crystalline powder.

Comment on solubility

Solubility of 2-(4-chlorophenyl)-3-phenyl-prop-2-enenitrile

The solubility of 2-(4-chlorophenyl)-3-phenyl-prop-2-enenitrile is a topic of interest due to its diverse applications in organic synthesis and pharmaceuticals. This compound exhibits limited solubility in polar solvents, while showing a greater affinity for non-polar solvents. Here are some key points regarding its solubility:

  • Polar Solvents: The compound tends to be insoluble or only sparingly soluble in polar solvents such as water and ethanol.
  • Non-Polar Solvents: It demonstrates enhanced solubility in organic solvents like benzene, chloroform, and hexane.
  • Temperature Dependency: Solubility can be affected by temperature, where increased temperatures may improve solubility in certain non-polar solvents.

In conclusion, the solubility characteristics of 2-(4-chlorophenyl)-3-phenyl-prop-2-enenitrile make it particularly relevant in organic chemistry, where solvent selection is crucial for desired reactivity and synthesis outcomes. Understanding these solubility properties is essential when designing experiments or processes involving this compound.

Interesting facts

Interesting Facts about 2-(4-Chlorophenyl)-3-phenyl-prop-2-enenitrile

2-(4-Chlorophenyl)-3-phenyl-prop-2-enenitrile, more commonly referred to in scientific circles as a member of the nitrile family, exhibits intriguing properties that are of significant interest in various fields of chemistry and material science.

Chemical Significance

  • Functional Group Importance: The presence of the nitrile functional group (-C≡N) is noteworthy as it enhances the compound's reactivity, making it suitable for various chemical transformations.
  • Diverse Applications: Compounds like this serve as intermediates in organic synthesis, thus playing a crucial role in the development of pharmaceuticals and agrochemicals.

Structural Characteristics

  • Substitution Patterns: The specific arrangement of the phenyl and chlorophenyl groups contributes to the compound's unique electronic properties, affecting how it interacts with biological systems.
  • Isomerism: The structural features allow for potential isomerism, which may influence physical and chemical characteristics, opening new avenues for exploration.

Research Insights

Current research involving 2-(4-Chlorophenyl)-3-phenyl-prop-2-enenitrile highlights its potential in:

  • Drug Development: Due to its reactive nature, it could be investigated as a scaffold for novel medicinal compounds.
  • Material Science: Its properties might be utilized in developing materials with specific functionalities, potentially leading to advancements in nanotechnology.

As a versatile compound, 2-(4-Chlorophenyl)-3-phenyl-prop-2-enenitrile not only expands our understanding of nitrile compounds but also embodies the constant evolution of chemical research aimed at addressing modern challenges in science and industry.

Synonyms
NCIOpen2_005532
NCIOpen2_005654
DTXSID601243087
AKOS030230977
DB-080843
4-Chloro-I+/--(phenylmethylene)benzeneacetonitrile
(2Z)-2-(4-chlorophenyl)-3-phenylprop-2-enenitrile