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Chlorphenamine

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Identification
Molecular formula
C16H19ClNO
CAS number
132-22-9
IUPAC name
2-[(4-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine
State
State
Chlorphenamine is typically in a solid state at room temperature.
Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
357.00
Boiling point (Kelvin)
630.15
General information
Molecular weight
274.79g/mol
Molar mass
274.7850g/mol
Density
1.0900g/cm3
Appearence

Chlorphenamine, also known as Chlorpheniramine, typically appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 2-[(4-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine

The solubility of 2-[(4-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine can be considered in terms of its molecular structure and the interactions that govern solute-solvent compatibility. This compound, characterized by its complex aromatic system and aliphatic amine functionality, exhibits certain properties that affect its solubility:

  • Solvent Polarity: Overall, the solubility of organic compounds is significantly influenced by the polarity of the solvent. Generally, non-polar substances tend to dissolve well in non-polar solvents, while polar substances are better soluble in polar solvents.
  • Hydrogen Bonding: The presence of the amine group in this compound may contribute to hydrogen bonding with polar solvents, enhancing its solubility in certain conditions.
  • Aromatic Interactions: The multiple aromatic rings can also influence solubility strategy through π-π interactions; thus, polar aromatic solvents could promote better solubility.

However, due to its complex structure and potential steric hindrance, predicting solubility without experimental data may yield uncertain results. Factors such as temperature and the specific solvent used can have substantial effects on the behavior of this compound in solution.

In essence, while the detailed solubility characteristics of 2-[(4-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine would require further empirical investigation, understanding its polar and non-polar characteristics allows chemists to make informed predictions about its solubility in various environments.

Interesting facts

Interesting Facts about 2-[(4-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine

This fascinating compound is noteworthy for several reasons, offering both unique structural properties and intriguing potential applications:

  • Structural Uniqueness: The compound features a complex arrangement of rings and functional groups that enhance its pharmacological properties. The presence of a 4-chlorophenyl group gives it distinctive chemical behavior.
  • Pharmacological Potential: Research suggests that compounds like this may exhibit significant biological activities, making them candidates for drug development. Scientists are interested in their potential as therapeutic agents, especially in the treatment of psychiatric disorders.
  • Mechanism of Action: Understanding how this compound interacts at the molecular level can provide insights into its effectiveness and safety. Compounds with similar structures often target neurotransmitter receptors, which is crucial for their effects in the nervous system.
  • Importance in Synthetic Chemistry: The synthesis of this compound often involves multi-step organic reactions, showcasing the intricate skills of chemists in manipulating chemical structures to yield desired compounds.
  • Research Applications: With advancements in molecular biology, 2-[(4-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine could serve as a model compound for studying structure-activity relationships, guiding future modifications for enhanced efficacy.

As scientists continue to explore its properties, the potential for discovering even more applications remains vast. Environmentally conscious synthetic pathways and innovative modifications could lead to a new class of compounds stemming from this chemical inspiration.


In summary, 2-[(4-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine is not only an example of complex organic chemistry but also a beacon of hope in the realm of medicinal chemistry. With ongoing research, the full potential of this compound may someday be realized, further expanding our understanding of human health and disease.

Synonyms
Oprea1_032179
CBDivE_006372
dimethylaminoethyl p-chlorobenzhydryl ether