Skip to main content

2-[(4-chlorophenyl)methoxy]guanidine

ADVERTISEMENT
Identification
Molecular formula
C8H10ClN3O
CAS number
472981-92-9
IUPAC name
2-[(4-chlorophenyl)methoxy]guanidine
State
State

At room temperature, 2-[(4-chlorophenyl)methoxy]guanidine is typically in a solid state. The compound is stable under standard conditions and usually requires specific conditions to change its state.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
405.80
Boiling point (Kelvin)
678.95
General information
Molecular weight
201.64g/mol
Molar mass
201.6360g/mol
Density
1.3630g/cm3
Appearence

2-[(4-chlorophenyl)methoxy]guanidine typically appears as a crystalline solid. The color can vary depending on the specific batch and purity but it often ranges from white to pale yellow.

Comment on solubility

Solubility of 2-[(4-chlorophenyl)methoxy]guanidine

2-[(4-chlorophenyl)methoxy]guanidine, a compound known for its unique structure, exhibits interesting solubility characteristics. The solubility of a compound is influenced by various factors including its molecular structure, polarity, and the nature of solvents available. In the case of this compound:

  • Polarity: Due to the presence of the guanidine moiety, which is polar, alongside the 4-chlorophenyl and methoxy groups, the compound may display a moderate level of solubility in polar solvents.
  • Solvent Interaction: It is likely to be soluble in polar protic solvents such as methanol and ethanol but may have limited solubility in non-polar solvents due to its functional groups.
  • Hydrogen Bonding: The ability of the guanidine group to form hydrogen bonds can enhance solubility in aqueous environments, potentially leading to improved dissolution when mixed with water.

As a general rule, compounds that can engage in hydrogen bonding and have polar functionalities typically show better solubility profiles. It is essential to consider these factors when predicting the solubility behavior of 2-[(4-chlorophenyl)methoxy]guanidine in various solvent systems.

Overall, while definitive solubility data may vary and should be determined experimentally, the molecular components suggest a tendency towards moderate solubility in suitable solvents.

Interesting facts

Interesting Facts about 2-[(4-chlorophenyl)methoxy]guanidine

2-[(4-chlorophenyl)methoxy]guanidine is a fascinating compound that belongs to the class of guanidines, which are known for their varied biological activities. Here are some intriguing highlights:

  • Pharmaceutical Relevance: This compound can be of particular interest in medicinal chemistry due to its structural motifs, which are often associated with biological activity.
  • Mechanism of Action: Compounds similar to guanidines have been studied for their efficacy in modulating various physiological processes, making them potential candidates for drug development in areas like anti-inflammatory and antifungal therapies.
  • Structure-Activity Relationship (SAR): The presence of the chlorophenyl group suggests interesting interactions within biological systems, leading to enhanced activity due to electron-withdrawing effects.
  • Synthesis Approaches: The synthesis of this compound can involve advanced organic chemistry techniques, including substitution reactions that highlight the versatility of guanidine derivatives.
  • Safety Considerations: As with many chemical compounds, understanding the safety and handling procedures for 2-[(4-chlorophenyl)methoxy]guanidine is critical in laboratory settings.

In summary, 2-[(4-chlorophenyl)methoxy]guanidine exemplifies the intricate relationship between chemical structure and biological function, making it a compound of noteworthy interest for researchers and pharmaceutical scientists alike.

Synonyms
SCHEMBL10862647