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Chlorphenamine

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Identification
Molecular formula
C16H19ClN2S
CAS number
132-22-9
IUPAC name
2-(4-chlorophenyl)sulfanyl-N,N-diethyl-ethanamine
State
State

At room temperature, chlorphenamine is typically found in the form of a solid, specifically as crystalline powder.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
310.80
Boiling point (Kelvin)
583.95
General information
Molecular weight
274.80g/mol
Molar mass
274.8020g/mol
Density
1.1857g/cm3
Appearence

Chlorphenamine, commonly referred to as chlorpheniramine, appears as a white to slightly yellow crystalline powder. It is slightly soluble in water but soluble in alcohol and chloroform.

Comment on solubility

Solubility of 2-(4-Chlorophenyl)sulfanyl-N,N-diethyl-ethanamine

The solubility of 2-(4-chlorophenyl)sulfanyl-N,N-diethyl-ethanamine can be influenced by several factors, including its molecular structure and environmental conditions. Understanding these aspects can lead to better predictions and applications in various fields.

Factors Affecting Solubility

  • Polarity of the Compound: This compound contains both nonpolar (ethyl groups) and polar (chlorine atom, nitrogen atom) functional groups, which can affect its interaction with solvents.
  • Type of Solvent: Like dissolves like. The solubility can vary greatly between polar solvents such as water and nonpolar solvents such as hexane. For instance, it may be more soluble in organic solvents than in aqueous solutions.
  • Temperature: Increasing temperature often enhances solubility for solid compounds. Therefore, conducting experiments at various temperatures can yield interesting results.

General Observations on Solubility

While specific solubility data for this compound may be limited, it is essential to consider that:

  • Compounds with similar structural features often show that they have limited water solubility but may dissolve readily in organic solvents.
  • The presence of the chlorophenyl group may introduce some level of aromatic character that often contributes to solubility in organic media.
  • Interactions such as hydrogen bonding, particularly due to the nitrogen atom, could influence the solubility profile.

In summary, determining the exact solubility of 2-(4-chlorophenyl)sulfanyl-N,N-diethyl-ethanamine requires considering the context of solvent choice and environmental parameters. A detailed experimental approach is typically necessary to provide precise solubility data for this intriguing compound.

Interesting facts

Exploring the Fascinating World of 2-(4-Chlorophenyl)sulfanyl-N,N-diethyl-ethanamine

2-(4-Chlorophenyl)sulfanyl-N,N-diethyl-ethanamine, often simply referred to by its structural characteristics, is a compound that piques the interest of chemists and researchers alike due to its unique functional groups and potential applications. Here are some engaging facts about this intriguing compound:

  • Functional Diversity: This compound includes a sulfonyl group and a chlorophenyl unit, contributing to its chemical reactivity and offering pathways for various functionalization.
  • Pharmacological Potential: With its amine structure, it holds promise in medicinal chemistry. Compounds similar to this one are often explored for their biological activity, including potential effects in neuropharmacology.
  • Properties of Sulfur: The inclusion of sulfur, particularly in the form of a sulfanyl group, can impart interesting properties, such as increased lipophilicity, which may enhance the ability of the compound to permeate biological membranes.
  • Simple to Synthesize: Often, compounds like these can be synthesized through relatively straightforward reactions, making them accessible for laboratory studies and further exploration in synthetic chemistry.
  • Environmental Chemistry: Investigating the environmental impact and degradation pathways of such compounds is crucial, especially as researchers strive for greener chemistry practices and assess the safety of new chemical entities.

As our understanding of the chemical landscape expands, compounds like 2-(4-Chlorophenyl)sulfanyl-N,N-diethyl-ethanamine will continue to serve as a bridge between various fields, inspiring new hypotheses, experiments, and ultimately, innovative solutions!

Synonyms
14214-33-6
2-(4-Chlorophenylthio)triethylamine
CPTA
DTXSID90161952
DTXCID9084443
2-(4-chlorophenyl)sulfanyl-N,N-diethylethanamine
Amchem 72-A42
Triethylamine, 2-((p-chlorophenyl)thio)-
Ethanamine,2-((4-chlorophenyl)thio)-N,N-diethyl-
SCHEMBL3422695
2-(4-chlorophenylthio)-triethylamine
2-((4-Chlorophenyl)thio)-N,N-diethylethan-1-amine
Ethanamine, 2-((4-chlorophenyl)thio)-N,N-diethyl-
N-{2-[(4-chlorophenyl)sulfanyl]ethyl}-N,N-diethylamine
Z103718958