Skip to main content

Roxarsone

ADVERTISEMENT
Identification
Molecular formula
C8H8AsNO5
CAS number
121-19-7
IUPAC name
2-[(4-dihydroxyarsanylbenzoyl)amino]acetic acid
State
State

At room temperature, Roxarsone is in a solid state. It is commonly used in its powder form.

Melting point (Celsius)
207.00
Melting point (Kelvin)
480.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
263.06g/mol
Molar mass
263.0640g/mol
Density
1.7300g/cm3
Appearence

Roxarsone appears as a light tan colored solid under normal conditions. It is typically found as a crystalline powder.

Comment on solubility

Solubility of 2-[(4-dihydroxyarsanylbenzoyl)amino]acetic acid

The solubility of 2-[(4-dihydroxyarsanylbenzoyl)amino]acetic acid, a compound with unique chemical properties, can be characterized by several important factors:

  • Polarity: This compound contains multiple hydroxyl groups, which generally enhance its ability to dissolve in polar solvents such as water.
  • Hydrogen Bonding: The presence of hydroxyl groups enables strong hydrogen bonding with water molecules, increasing its solubility.
  • Overall Structure: The structural configuration plays a crucial role; the ability of the compound to adopt various conformations can influence its solubility profile.
  • pH Influence: Solubility may also vary with changes in pH, as protonation or deprotonation of functional groups can alter solubility characteristics.

In many cases, it is noted that aromatic compounds can exhibit low solubility in water due to hydrophobic interactions, but the presence of polar substituents, such as hydroxyl groups in this compound, significantly mitigates this issue.

To summarize, the solubility of 2-[(4-dihydroxyarsanylbenzoyl)amino]acetic acid can be primarily attributed to its functional groups and their interactions with the solvent environment:

  1. High solubility in polar solvents.
  2. Expected increased solubility with rising temperatures.
  3. Possibly lower solubility in non-polar solvents.

Overall, its solubility is a balance between hydrophilic interactions and the inherent characteristics of its aromatic structure.

Interesting facts

Interesting Facts about 2-[(4-Dihydroxyarsanylbenzoyl)amino]acetic Acid

2-[(4-Dihydroxyarsanylbenzoyl)amino]acetic acid is a fascinating compound that embodies the complexity of organoarsenic chemistry. Below are some insightful highlights about this intriguing substance:

  • Unique Structure: The compound features an arsenic atom, which is relatively rare in organic molecules. This element enhances the compound's biological activity and reactivity, leading to a diverse range of chemical behaviors.
  • Biological Applications: Organoarsenic compounds, including this one, have shown potential in medicinal chemistry. They have been researched for their use in therapies against various diseases, including certain types of cancer.
  • Antioxidant Properties: With two hydroxyl groups in its structure, this compound is believed to exhibit significant antioxidant activities. The presence of these functional groups can neutralize free radicals, providing potential health benefits.
  • Analytical Importance: The compound's unique characteristics make it a valuable marker in environmental studies, especially concerning arsenic contamination in water sources. It can serve as an indicator of organic arsenic species in various analyses.
  • Chemical Synthesis: The synthesis of 2-[(4-dihydroxyarsanylbenzoyl)amino]acetic acid can be a complex process, often requiring careful control of reaction conditions to achieve purity and desired yield. This highlights the compound's importance in demonstrating advanced synthetic techniques in organic chemistry.

In summary, 2-[(4-dihydroxyarsanylbenzoyl)amino]acetic acid is not just another compound; it is a bridge between inorganic and organic chemistry, displaying various properties that offer exciting possibilities for research and applications. As one delves deeper into the world of organoarsenic compounds, one cannot help but appreciate the intricate role these compounds play in both nature and industry.

Synonyms
5425-20-7
HIPPURIC ACID, p-(DIHYDROXYARSINO)-
PJT4TD490O
p-(Dihydroxyarsino)-hippuric acid
NSC-12726
p-(Dihydroxyarsino)hippuric acid
NSC 12726
UNII-PJT4TD490O
ANTINEOPLASTIC-12726
DTXSID80202601
NSC12726