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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-[4-(dimethylamino)phenyl]-N-(1-methyl-2-phenyl-ethyl)acetamide
State
State

At room temperature, Lidocaine is in a solid crystalline state, often formed as a powder. However, it is commonly utilized in medicinal preparations as a liquid solution.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0300g/cm3
Appearence

Lidocaine is typically a white crystalline powder that is odorless. It is often available in oil form when warmed, which is colourless or pale yellow.

Comment on solubility

Solubility of 2-[4-(dimethylamino)phenyl]-N-(1-methyl-2-phenyl-ethyl)acetamide

The compound 2-[4-(dimethylamino)phenyl]-N-(1-methyl-2-phenyl-ethyl)acetamide, often referred to for its complex structure, showcases varying solubility characteristics depending on the solvents used.

Key Aspects of Solubility:

  • Polar solvents: This compound is known to exhibit a significant degree of solubility in polar solvents like water and methanol due to the presence of the amide functional group, which can engage in hydrogen bonding.
  • Non-polar solvents: In contrast, it shows lower solubility in non-polar solvents, such as hexane or toluene, as its structure contains aromatic groups that enhance hydrophobic interactions.
  • Temperature factors: The solubility can also increase with temperature, making it important to consider conditions during experimentation and application.

As with many organic compounds, the solubility is significantly influenced by factors such as pH, temperature, and the presence of other solutes. These variables can lead to changes in solubility behavior which are crucial for practical applications in pharmaceuticals and chemical synthesis. Thus, understanding the solubility profile is key to optimizing the use of 2-[4-(dimethylamino)phenyl]-N-(1-methyl-2-phenyl-ethyl)acetamide in various chemical processes.

Interesting facts

Interesting Facts about 2-[4-(dimethylamino)phenyl]-N-(1-methyl-2-phenyl-ethyl)acetamide

This compound, commonly referred to within the realm of medicinal chemistry, is an intriguing member of the amide family. Its unique structure gives rise to a variety of potential applications in pharmaceuticals and beyond. Here are some fascinating insights:

  • Pharmacological Potential: The compound exhibits properties that are of interest in the development of new drugs, particularly in the treatment of pain and inflammation.
  • Structural Composition: Its backbone features a dimethylamino group which is known to enhance its bioactivity, allowing for better permeability across biological membranes.
  • Target Specificity: The phenyl-ethyl moiety in its structure contributes to the compound's affinity towards various biological targets, making it significant in receptor-binding studies.
  • Research Applications: This compound serves as a model for synthesizing similar amides with tailored properties, allowing chemists to explore different functionalizations.
  • Multi-Functional Usage: Beyond medicinal uses, derivatives of this compound are being investigated for their roles in materials science and as intermediates in organic synthesis.

In the words of chemist and pioneer Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” This compound embodies that spirit, showcasing how detailed structural variations can lead to a myriad of research avenues. As new studies emerge, the full potential of 2-[4-(dimethylamino)phenyl]-N-(1-methyl-2-phenyl-ethyl)acetamide continues to unfold.

Synonyms
N,N-Dimethylphepracet
IEM 508
18464-53-4
2-(p-(Dimethylamino)phenyl)-N-(alpha-methylphenethyl)acetamide
BRN 2947142
Benzeneacetamide, 4-(dimethylamino)-N-(1-methyl-2-phenylethyl)-
ACETAMIDE, 2-(P-(DIMETHYLAMINO)PHENYL)-N-(ALPHA-METHYLPHENETHYL)-
2-[4-(dimethylamino)phenyl]-N-(1-phenylpropan-2-yl)acetamide
2-(4-(Dimethylamino)phenyl)-N-(1-phenylpropan-2-yl)acetamide
Cambridge id 5406300
Oprea1_342343
Oprea1_385728
MLS000569072
CHEMBL1597072
DTXSID60939862
HMS1581K02
HMS2570M14
2-(4-Dimethylamino-phenyl)-N-(1-methyl-2-phenyl-ethyl)-acetamide
NCGC00245103-01
SMR000174806
AB00084282-01
2-[4-(Dimethylamino)phenyl]-N-(1-phenylpropan-2-yl)ethanimidic acid