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Fluorometholone

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Identification
Molecular formula
C22H28FNO4
CAS number
426-13-1
IUPAC name
2-(4-ethoxy-3-fluoro-benzoyl)oxyethyl-diethyl-ammonium;chloride
State
State

At room temperature, Fluorometholone is in a solid state. Its stability and crystalline form make it suitable for pharmaceutical formulations.

Melting point (Celsius)
276.00
Melting point (Kelvin)
549.15
Boiling point (Celsius)
286.00
Boiling point (Kelvin)
559.15
General information
Molecular weight
376.45g/mol
Molar mass
376.4470g/mol
Density
1.0634g/cm3
Appearence

Fluorometholone typically appears as a white to off-white crystalline powder. It is insoluble in water, which affects its application in aqueous solutions, but it is freely soluble in acetone, alcohol, and chloroform.

Comment on solubility

Solubility of 2-(4-ethoxy-3-fluoro-benzoyl)oxyethyl-diethyl-ammonium chloride

The solubility of 2-(4-ethoxy-3-fluoro-benzoyl)oxyethyl-diethyl-ammonium;chloride can be influenced by various factors, primarily due to the presence of both organic and ionic components in its structure. In general, quaternary ammonium compounds such as this one tend to exhibit certain solubility characteristics:

  • General Solubility: Typically, quaternary ammonium compounds are soluble in polar solvents such as water and alcohols due to their ionic nature.
  • Effect of Ionic Strength: The solubility may increase in the presence of other ions in solution, potentially enhancing the dissolution process.
  • Temperature Dependency: As with many compounds, solubility may also increase with temperature, allowing for greater dissolution in heated solvent systems.

Considering these factors, we emphasize the importance of understanding the solvent's properties. Higher polar solvents are more likely to provide a suitable environment for dissolution. In practical applications, factors such as pH and the presence of co-solvents can significantly modulate the solubility behavior of this compound.

In summary, while the solubility of 2-(4-ethoxy-3-fluoro-benzoyl)oxyethyl-diethyl-ammonium;chloride is generally favorable in polar solvents, factors like temperature, ionic strength, and pH must always be taken into account.

Interesting facts

Interesting Facts About 2-(4-Ethoxy-3-fluoro-benzoyl)oxyethyl-diethyl-ammonium Chloride

The compound 2-(4-Ethoxy-3-fluoro-benzoyl)oxyethyl-diethyl-ammonium chloride is a fascinating example of a quaternary ammonium compound, known for its unique properties and applications. Here are some noteworthy points about this intriguing compound:

  • Novel Structure: This compound features a quaternary ammonium moiety, which is characterized by a central nitrogen atom bonded to four carbon atoms. This structure contributes to its ionic character and solubility in polar solvents.
  • Antimicrobial Activity: Many quaternary ammonium compounds exhibit impressive antimicrobial properties, making them useful in various disinfectants and antiseptics. The presence of the ethoxy and fluoro groups may enhance its activity against certain pathogens.
  • Drug Delivery Systems: The compound may play a role in targeted drug delivery, thanks to its biocompatibility. Its structure could facilitate the incorporation of therapeutic agents, potentially improving their bioavailability.
  • Research Applications: Scientists are increasingly exploring compounds like this for their potential applications in materials science, such as in the development of new polymers or surfactants.

The combination of the ethoxy and fluoro substituents in its structure not only makes this compound interesting but also offers possible avenues for research and development in fields ranging from pharmaceuticals to nanotechnology. As emphasized by the quote from Dr. Jane Goodall, "What you do makes a difference, and you have to decide what kind of difference you want to make." In the case of this compound, research and innovations can lead to significant advances in health and materials science.

In conclusion, 2-(4-Ethoxy-3-fluoro-benzoyl)oxyethyl-diethyl-ammonium chloride represents a remarkable intersection of chemistry and application, highlighting the broad potential of quaternary ammonium compounds in modern research.

Synonyms
4-Ethoxy-3-fluorobenzoic acid 2-(diethylamino)ethyl ester hydrochloride
5710-74-7
Fluoro-3 ethoxy-4 benzoate de beta-diethylaminoethyle chlorhydrate [French]
BENZOIC ACID, 4-ETHOXY-3-FLUORO-, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE
Fluoro-3 ethoxy-4 benzoate de beta-diethylaminoethyle chlorhydrate