N-(4-ethoxyphenyl)-N',N''-bis(4-methoxyphenyl)guanidine

Identification

Molecular formula

C₂₃H₂₆N₂O₃

CAS number

Not assigned

IUPAC name

2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine

State

At room temperature, this compound is typically found as a solid due to its large molar mass and strong intermolecular forces arising from its aromatic components and the polar guanidine group.

Melting point (Celsius)

191.00

Melting point (Kelvin)

464.15

Boiling point (Celsius)

570.30

Boiling point (Kelvin)

843.50

General information

Molecular weight

390.48g/mol

Molar mass

390.4820g/mol

Density

1.1850g/cm³

Appearence

The compound is typically a crystalline solid, often exhibiting a white to off-white color. It can appear as a powder or very small crystals that reflect light and may have a slight sheen.

Comment on solubility

Solubility of 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine

The solubility of 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine is influenced by its complex molecular structure. Here are some key points regarding its solubility:

Aromatic Nature: The presence of phenyl groups contributes to hydrophobic interactions, which can limit solubility in polar solvents.
Ethoxy and Methoxy Substituents: The ethoxy and methoxy groups can enhance solubility in organic solvents due to their ability to engage in hydrogen bonding and dipole interactions.
Comparison with Guanidine: While guanidine itself is typically more soluble in water, the bulky aromatic substituents in this compound may reduce overall solubility when compared to simpler guanidine derivatives.

Generally, the compound is expected to have:

Moderate solubility in polar organic solvents (like ethanol and methanol).
Lower solubility in water due to its hydrophobic aromatic components.

In practice, the solubility will also depend on conditions such as temperature and the presence of cosolvents. As with many organic compounds, the interpretation of solubility might vary based on specific experimental setups. Thus, one must always conduct laboratory assessments to determine precise solubility values.

Interesting facts

Interesting Facts about 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine

This remarkable compound belongs to the class of guanidines, which are often recognized for their diverse biological activities and applications. Here are some intriguing points about 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine:

Pharmaceutical Potential: Guanidine derivatives, including this compound, have been studied for their potential therapeutic effects. They may play a role in the development of medications for various conditions, particularly in the realm of neuropharmacology.
Structure-Activity Relationship: The unique structure featuring both ethoxy and methoxy groups enhances the compound's solubility and interaction with biological targets, highlighting the importance of molecular design in medicinal chemistry.
Research Applications: Researchers have been investigating guanidine derivatives in relation to their capabilities as anti-inflammatory, antioxidant, and even anti-cancer agents. There's a growing interest in their effects on cellular signaling pathways.
Versatility in Chemistries: The guanidine framework allows for modifications that can lead to entirely new compounds, making it a valuable scaffold in organic synthesis and drug development.
Mechanisms of Action: While the exact mechanisms of action of this specific compound are still under investigation, guanidine compounds are generally known to affect ion channels and neurotransmitter systems, making them of great interest in neurobiology.

In summary, 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine is more than just a compound; it embodies the intersection of organic chemistry and pharmaceutical science. As research continues to unveil its potential, this compound may contribute to significant advancements in medicinal therapies.

Synonyms

NS00002185