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Propylthiouracil

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Identification
Molecular formula
C7H10N2O2S
CAS number
51-52-5
IUPAC name
2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine;hydrochloride
State
State

At room temperature, Propylthiouracil is a solid. It is often supplied in a powdered form which makes it easier to handle in various chemical reactions and applications.

Melting point (Celsius)
219.00
Melting point (Kelvin)
492.15
Boiling point (Celsius)
249.00
Boiling point (Kelvin)
522.15
General information
Molecular weight
170.24g/mol
Molar mass
170.2430g/mol
Density
1.3000g/cm3
Appearence

This compound exists as a crystalline powder. Typically, it appears white or off-white in color. Such appearance is common for this type of chemical compound, which is often used for analytical and compound preparation purposes in the laboratory settings.

Comment on solubility

Solubility of 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine; hydrochloride

The solubility of 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine; hydrochloride can be influenced by several key factors:

  • Polarity: This compound is likely to exhibit varying degrees of solubility in polar and non-polar solvents due to the presence of multiple functional groups.
  • Temperature: Increased temperatures often enhance solubility for many compounds; however, this can depend on the specific interactions of the hydrochloride salt.
  • pH Levels: As a hydrochloride salt, the solubility may increase in acidic conditions, leading to higher dissolution rates.

It’s important to note that, generally speaking, guanidine derivatives tend to be more soluble in water compared to their non-salt forms due to ionization effects in aqueous solutions. In practice, you may find that:

  • The hydrochloride form is likely to be more soluble than the un-ionized base.
  • Aqueous solubility may be significant, but exact values would require empirical measurement or data from safety data sheets.

In summary, while the solubility of this compound is affected by its structural characteristics and environmental factors, its hydrochloride form typically enhances solubility compared to its neutral form.

Interesting facts

Interesting Facts About 2-(4-Ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine Hydrochloride

This compound, known as 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine hydrochloride, is a fascinating example of organic chemistry with potential applications in medicinal chemistry and pharmacology. Here are some intriguing aspects to consider:

  • Pharmaceutical Potential: Compounds like this are often studied for their bioactive properties, which can lead to the development of new medications. Their complex structure might influence various biological targets in the body, paving the way for innovative therapies.
  • Chemical Structure: The presence of both ethoxy and methoxy groups indicates that the compound may exhibit interesting solubility and reactivity attributes, making it a candidate for studies on how substituent groups affect biological activity.
  • Research Applications: Beyond pharmaceuticals, compounds of this nature are valuable in academic laboratories for research into new chemical reactions and the synthesis of novel materials.
  • Synthetic Pathways: Understanding the synthetic routes to obtain this guanidine derivative can reveal much about the field of organic synthesis, where reaction conditions and reagents play critical roles in yielding the desired products.
  • Guanidine Framework: The guanidine moiety is well-known for its basicity and ability to form hydrogen bonds, which can affect the compound’s interaction with various biological molecules.

In summary, while 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine hydrochloride may initially seem daunting, the intricacies of its structure and the implications of its properties make it a rich topic for study. As researchers delve deeper, they uncover not only potential applications but also fundamental chemical principles that underline the behavior of organic compounds.

Synonyms
Acoin
Guanicaine
537-05-3
Acoin hydrochloride
Phenodianisyl
Acoine
Akoin hydrochlorid
Phenodianisyl hydrochloride
Akoin hydrochlorid [German]
Dianisyl-monophenethylguanidine hydrochloride
2-(4-Ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine hydrochloride
Diparaanisyl-monophenethyl-guanidin-hydrochlorid [German]
Diparaanisyl-monophenethyl-guanidin-hydrochlorid
alpha,gamma-Di-p-anisyl-beta-(ethoxyphenyl)guanidine hydrochloride
DTXSID60201955
N,N'-Bis(4-methoxyphenyl)-N''-(4-ethoxyphenyl)guanidine hydrochloride
Guanidine, 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)-, hydrochloride
Guanidine, 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)-, hydrochloride (9CI)
GUANIDINE, 2-(p-ETHOXYPHENYL)-1,3-BIS(p-METHOXYPHENYL)-, HYDROCHLORIDE
DTXCID90124446
2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine;hydrochloride
AKOS040750110