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2-(4-Ethoxyphenyl)sulfanyl-1-[2-(1-piperidyl)ethyl]benzimidazole

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Identification
Molecular formula
C22H25N3O S
CAS number
1354054-50-9
IUPAC name
2-(4-ethoxyphenyl)sulfanyl-1-[2-(1-piperidyl)ethyl]benzimidazole
State
State

At room temperature, this compound is typically in the form of a solid. Its physical state might vary slightly based on environmental factors like temperature and humidity but it remains predominantly solid under standard conditions.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
522.00
Boiling point (Kelvin)
795.15
General information
Molecular weight
381.53g/mol
Molar mass
381.5280g/mol
Density
1.2600g/cm3
Appearence

This compound typically appears as a solid, with color ranging from off-white to pale yellow. The precise appearance may vary depending on the specific conditions of synthesis and any impurities present.

Comment on solubility

Solubility of 2-(4-ethoxyphenyl)sulfanyl-1-[2-(1-piperidyl)ethyl]benzimidazole

The solubility of 2-(4-ethoxyphenyl)sulfanyl-1-[2-(1-piperidyl)ethyl]benzimidazole can be influenced by several factors, particularly its molecular structure. Understanding the solubility characteristics of this compound provides insight into its potential applications and behavior in various environments.

Key Points on Solubility:

  • Polarity: The presence of both a sulfanyl group and ethoxy substituent suggests that the compound may exhibit moderate polarity, which can affect how it interacts with solvents.
  • Solvent Compatibility: Generally, compounds with similar polarities to solvents dissolve better. For this compound, it may have good solubility in organic solvents like ethanol and acetone while displaying poor solubility in non-polar solvents.
  • Temperature Effects: Solubility can vary significantly with temperature; as temperature increases, many compounds tend to become more soluble in their respective solvents.
  • pH Influence: Given the presence of functional groups, the solubility of this compound may also be affected by the pH of the solution, which could impact ionization states and thus solubility.

In summary, while specific solubility data for 2-(4-ethoxyphenyl)sulfanyl-1-[2-(1-piperidyl)ethyl]benzimidazole might vary, it is important to consider the above factors when assessing its solubility in different environments. A thorough understanding of these properties is crucial for optimizing its use in pharmaceuticals and other applications.

Interesting facts

Interesting Facts about 2-(4-ethoxyphenyl)sulfanyl-1-[2-(1-piperidyl)ethyl]benzimidazole

This compound is a remarkable example of a benzodiazepine derivative, formally known as a benzimidazole. Its structure includes a piperidine and an ethoxyphenyl group, contributing to its potential biological activity. Here are some fascinating aspects of this compound:

  • Diverse Applications: Compounds like this one have garnered attention due to their potential applications in pharmacology, particularly as therapeutic agents. They can influence various biological pathways and may have antitumor, antiviral, or analgesic properties.
  • Structural Features: The presence of both sulfur and nitrogen atoms within the molecule illustrates the versatility of organic synthesis, allowing for the creation of compounds with varied reactivity and interactions in biological systems.
  • Research Potential: As a benzimidazole derivative, this compound may play a crucial role in the development of new medications. It can serve as a scaffold for further modifications, potentially enhancing activity against specific diseases.
  • Interactive Nature: The piperidine moiety is known to enhance the pharmacokinetic profile of drugs, improving solubility and bioavailability. This makes the compound an interesting subject for further studies aimed at optimizing therapeutic compounds.

From a scientific perspective, understanding the chemical behavior and the pharmacodynamics of such compounds can lead to significant advancements in medicinal chemistry. The intriguing nature of its molecular structure helps us appreciate the intricate balance between chemical design and biological efficacy. Its potential therapeutic benefits underscore the importance of ongoing research in the field.


As you explore this compound further, consider its synthesis and how slight modifications could lead to new derivatives with improved efficacy or reduced side effects. This highlights the exciting nature of chemical research and the endless possibilities that await in the realm of medicinal compounds!

Synonyms
BRN 0851936
13451-95-1
BENZIMIDAZOLE, 2-((p-ETHOXYPHENYL)THIO)-1-(2-PIPERIDINOETHYL)-
2-((p-Ethoxyphenyl)thio)-1-(2-piperidinoethyl)benzimidazole
DTXSID90158766
DTXCID1081257
5-23-11-00294 (Beilstein Handbook Reference)
2-[(4-Ethoxyphenyl)sulfanyl]-1-[2-(1-piperidinyl)ethyl]-1H-benzimidazole