Interesting facts
Interesting Facts about 2-(4-Fluorophenyl)acetic Acid
2-(4-Fluorophenyl)acetic acid is a fascinating compound that belongs to the family of aromatic carboxylic acids, renowned for their diverse applications in various fields of chemistry and pharmacology. Here are some engaging facts about this compound:
- Pharmaceutical Relevance: This compound is notable in the pharmaceutical industry as a precursor in the synthesis of drugs, particularly anti-inflammatory agents. Its unique structure contributes to the activity of these therapeutics.
- Fluorine's Role: The presence of the –F (fluoro) group enhances the compound's chemical properties significantly. Fluorine substitutions often improve a molecule's bioavailability, stability, and potency.
- Research Interest: Scientists are keenly interested in developing derivatives of 2-(4-fluorophenyl)acetic acid for enhanced pharmacological effects. Research studies frequently explore its potential benefits and mechanisms of action.
- Organic Synthesis: It serves as a valuable building block in organic synthesis. Chemists utilize this compound to create various other complex molecules through reactions such as coupling and esterification.
- Analytical Techniques: Researchers often employ advanced analytical techniques, such as NMR and mass spectrometry, to study the structure and dynamics of this compound, revealing insights that may lead to new discoveries.
In summary, 2-(4-fluorophenyl)acetic acid embodies the intricate relationship between structure and function in chemistry, demonstrating how subtle changes in molecular composition can lead to significant enhancements in utility and application.
Synonyms
4-FLUOROPHENYLACETIC ACID
405-50-5
2-(4-Fluorophenyl)acetic acid
p-Fluorophenylacetic acid
(4-Fluorophenyl)acetic acid
Benzeneacetic acid, 4-fluoro-
4-Fluorobenzeneacetic acid
Acetic acid, (p-fluorophenyl)-
(p-Fluorophenyl)acetic acid
MFCD00004343
Ba 2821
S5YJV7CAZ1
NSC 402
NSC-402
EINECS 206-972-4
AI3-52627
(4-fluoro-phenyl)-acetic acid
DTXSID0059956
2-(4-fluorophenyl)-acetic acid
FLUOROPHENYLACETIC ACID, P-
P-FLUOROPHENYLACETIC ACID [MI]
UNII-S5YJV7CAZ1
4-fluorophenyl acetic acid
Maybridge1_006666
p-fluorophenyl acetic acid
4-fluorophenyl-acetic acid
4-Fluoro phenylacetic acid
4-fluoro phenyl acetic acid
4-fluoro-phenyl-acetic acid
Pipamperone metabolite M-XII
SCHEMBL104746
NSC402
DTXCID5039771
4-Fluorophenylacetic acid, 98%
HMS560G22
MGKPFALCNDRSQD-UHFFFAOYSA-
acetic acid, 2-(4-fluorophenyl)-
STK499017
AKOS000119591
Acetic acid, (p-fluorophenyl)-(8CI)
BH-0409
CS-W001955
AC-10975
BP-20574
PD119085
SY001347
DB-006819
F0206
NS00015559
EN300-20216
AH-034/32462009
Q27288702
F2191-0056
Z104477312
InChI=1/C8H7FO2/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5H2,(H,10,11)
Solubility of 2-(4-fluorophenyl)acetic acid
2-(4-fluorophenyl)acetic acid, characterized by its unique structure, displays notable solubility properties that warrant attention. Generally, this compound is considered to be:
One of the key factors affecting the solubility of 2-(4-fluorophenyl)acetic acid is its acidic functional group. This group tends to ionize in water, leading to enhanced solubility due to:
Moreover, the presence of the fluorine atom introduces a level of electronegativity that can influence the compound's interactions with solvents. As stated, “Like dissolves like,” which emphasizes the importance of matching solvent polarity to that of the solute.
In summary, while 2-(4-fluorophenyl)acetic acid shows promising solubility in certain media, its behavior is complex and influenced by both its molecular structure and the nature of the solvent.