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Iodothyramine

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Identification
Molecular formula
C8H6INO4
CAS number
84903-15-1
IUPAC name
2-(4-hydroxy-3-iodo-5-nitro-phenyl)acetic acid
State
State

At room temperature, iodothyramine exists as a solid. It has a relatively high melting point, indicating it forms a stable solid lattice structure at room temperature.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
311.06g/mol
Molar mass
311.0620g/mol
Density
2.2200g/cm3
Appearence

Iodothyramine appears as a crystalline solid with a cream to light yellow color. As with many organic compounds containing iodine, the shade might vary slightly depending on the particular crystal size and purity.

Comment on solubility

Solubility of 2-(4-hydroxy-3-iodo-5-nitro-phenyl)acetic acid

The solubility of the compound 2-(4-hydroxy-3-iodo-5-nitro-phenyl)acetic acid exhibits characteristics influenced by its molecular structure. This compound contains both hydrophilic and hydrophobic functional groups, which significantly affects its solubility in various solvents.

Key Factors Influencing Solubility:

  • Polar Functional Groups: The presence of the hydroxyl (-OH) group contributes to enhanced solubility in polar solvents such as water. The ability of hydroxyl groups to form hydrogen bonds with water molecules is a crucial factor.
  • Non-Polar Regions: Conversely, the iodo and nitro groups add non-polar characteristics, which can decrease solubility in highly polar solvents.
  • pH Sensitivity: The acidic nature of the carboxylic acid (-COOH) may influence solubility variations. At different pH levels, the compound can ionize, potentially increasing its solubility in alkaline conditions.

In summary, "the solubility of 2-(4-hydroxy-3-iodo-5-nitro-phenyl)acetic acid is conditional" on solvent polarity and environmental pH. This balance between polar and non-polar components leads to a complex solubility profile that requires careful consideration in practical applications.

Interesting facts

Interesting Facts about 2-(4-hydroxy-3-iodo-5-nitro-phenyl)acetic acid

2-(4-hydroxy-3-iodo-5-nitro-phenyl)acetic acid, a noteworthy compound, is a derivative of phenyl acetic acid that exhibits impressive biological activity. This compound is significant in pharmacology and medicinal chemistry for various reasons:

  • Pharmaceutical Applications: This compound serves as a precursor for several pharmaceuticals, highlighting its role in drug synthesis and development.
  • Antibacterial Properties: Research indicates that compounds with similar structures often exhibit antibacterial properties, making them potential candidates for new antibiotic formulations.
  • Structural Diversity: The presence of diverse functional groups, such as hydroxyl, iodo, and nitro, contributes to its structural uniqueness and influences its reactivity and interaction with biological targets.
  • Research Interest: As scientists continue to explore the various effects of halogenated compounds on human health, this compound remains a point of interest due to its iodine substituent, which may enhance biological interactions.

It is fascinating to note how modifications to a simple aromatic structure can lead to significant enhancements in activity and selectivity. As one prominent researcher stated, “The future of drug discovery lies in the understanding of complex molecular interactions.” This compound embodies the essence of such explorations, bridging the gap between design and application in the ever-evolving field of chemistry.

Furthermore, the study of this compound contributes to our broader knowledge of phenylacetic acids and their derivatives, paving the way for innovations in therapeutic agents. As more studies are conducted, we can look forward to uncovering even more intriguing aspects of this compound.

Synonyms
2646-51-7
Nip-hapten
2-(4-hydroxy-3-iodo-5-nitrophenyl)acetic acid
(4-hydroxy-3-iodo-5-nitrophenyl)acetic acid
4-Hydroxy-3-iodo-5-nitrophenylacetic acid
NITROHYDROXYIODOPHENYLACETATE
Benzeneacetic acid, 4-hydroxy-3-iodo-5-nitro-
Nitrohydroxyiodophenylacetic acid
(4-hydroxy-5-iodo-3-nitrophenyl)acetic acid
4-hydroxy-3-iodo-5-nitro-benzeneacetic acid
4-HYDROXY-3-IODO-5-NITRO-PHENYLACETIC ACID
NIP-OH
SCHEMBL378767
CHEBI:53798
DTXSID70181057
KPWFDZXSCIFGNO-UHFFFAOYSA-N
AKOS024374943
4-hydroxy-3-iodo-5-nitrobenzeneacetic acid
H20627
Q27124217