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Choline

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Identification
Molecular formula
C5H14NO
CAS number
62-49-7
IUPAC name
2-(4-hydroxyphenyl)ethyl-trimethyl-ammonium
State
State

Choline is typically found in a liquid form at room temperature, although it can exist as solids in certain derivatives or salt forms.

Melting point (Celsius)
-74.70
Melting point (Kelvin)
198.45
Boiling point (Celsius)
118.00
Boiling point (Kelvin)
391.15
General information
Molecular weight
121.18g/mol
Molar mass
121.1790g/mol
Density
1.0662g/cm3
Appearence

Choline appears as a hygroscopic, colorless, and semi-solid at room temperature. It is a quaternary ammonium compound with a fishy odor.

Comment on solubility

Solubility of 2-(4-hydroxyphenyl)ethyl-trimethyl-ammonium

The solubility of 2-(4-hydroxyphenyl)ethyl-trimethyl-ammonium is influenced by its ionic nature and structural characteristics. This compound possesses a quaternary ammonium group, which generally enhances solubility in polar solvents. Here are some key points about its solubility:

  • Polar Solvents: Typically, compounds with quaternary ammonium structures dissolve well in water and other polar solvents due to the interaction between the ionic ammonium group and water molecules.
  • Non-Polar Solvents: In contrast, the solubility in non-polar solvents may be quite low, as the hydrophobic aromatic region can hinder interactions with non-polar media.
  • pH Sensitivity: The solubility can also be affected by the pH of the solution; at varying pH levels, the degree of ionization of different functional groups may change.
  • Applications: The solubility characteristics make this compound beneficial in various applications, such as in pharmaceuticals or materials science, where the dispersion in a particular solvent is paramount.

In conclusion, the solubility of 2-(4-hydroxyphenyl)ethyl-trimethyl-ammonium is primarily influenced by its ionic character, making it more soluble in polar solvents compared to non-polar ones.

Interesting facts

Interesting Facts about 2-(4-Hydroxyphenyl)ethyl-trimethyl-ammonium

2-(4-Hydroxyphenyl)ethyl-trimethyl-ammonium, often referred to in the scientific community by its more common name, is a fascinating compound that attracts interest for its unique structure and properties. Here are some intriguing aspects to consider:

  • Functional Group Diversity: The compound features both a hydroxyphenyl group and a quaternary ammonium functional group, presenting an excellent study of how various functional groups can influence chemical properties and biological activities.
  • Biological Relevance: Quaternary ammonium compounds like this one are often explored for their applications in antimicrobial properties. Their ability to disrupt microbial cell membranes makes them valuable in pharmaceutical and medicinal chemistry.
  • Charge Distribution: Being a quaternary ammonium compound, it carries a permanent positive charge. This property enhances its solubility in water and allows for interactions with negatively charged biological molecules, which can be a topic of interest in drug design.
  • Research Applications: This compound is studied in various scientific fields including organic synthesis, material science, and medicinal chemistry. It serves as a model compound in exploring how structural modifications can affect biological activity.
  • Potential for Innovation: The structural configuration of this compound allows chemists to modify it further, paving the way for the development of new derivatives with potentially enhanced properties.

As with many chemical compounds, understanding 2-(4-hydroxyphenyl)ethyl-trimethyl-ammonium offers a window into the complex interactions that govern chemical behavior and biological function. The compound’s unique structure serves as a reminder of how interdisciplinary approaches in chemistry can lead to novel discoveries.

Synonyms
Candicine
6656-13-9
Candicin
2-(4-hydroxyphenyl)ethyl-trimethylazanium
4-Hydroxy-N,N,N-trimethylbenzeneethanaminium
AMMONIUM, (p-HYDROXYPHENETHYL)TRIMETHYL-
BRN 4133224
Benzeneethanaminium, 4-hydroxy-N,N,N-trimethyl-
DTXSID80901642
2-(4-hydroxyphenyl)ethyl-trimethyl-ammonium
DTXCID50946020
Benzeneethanaminium, 4-hydroxy-N,N,N-trimethyl-(9CI)
5V2TJ5H9Z8
CHEBI:3350
2-(4-hydroxyphenyl)-N,N,N-trimethylethanaminium
MLS001048976
SMR000386994
UNII-5V2TJ5H9Z8
BENZENEETHANAMINIUM,4-HYDROXY-N,N,N-TRIMETHYL-
SCHEMBL9561478
CHEMBL1186075
BDBM73699
cid_15127809
STL581350
AKOS030573561
NCGC00246201-01
[2-(4-hydroxyphenyl)ethyl]trimethylazanium
NS00094418
E87162
2-(4-hydroxyphenyl)ethyl-trimethylazanium;iodide
2-(4-hydroxyphenyl)ethyl-trimethyl-ammonium;iodide
2-(4-hydroxyphenyl)ethyl-trimethyl-azanium;iodide
2-(4-hydroxyphenyl)ethyl-trimethylammonium;iodide
Q5031710