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Ibuprofen thiohydroxamic acid

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Identification
Molecular formula
C14H23NO2S
CAS number
5162-56-5
IUPAC name
2-(4-isobutyl-3-methyl-phenyl)sulfanylethanehydroxamic acid
State
State

At room temperature, this compound is in a solid state. Specific characteristics such as its crystalline form contribute to this state.

Melting point (Celsius)
76.00
Melting point (Kelvin)
349.15
Boiling point (Celsius)
372.85
Boiling point (Kelvin)
646.00
General information
Molecular weight
263.38g/mol
Molar mass
263.3750g/mol
Density
1.1780g/cm3
Appearence

Ibuprofen thiohydroxamic acid typically appears as a white to off-white crystalline powder. Its color and form can slightly vary based on purity and specific synthesis methods, but it is generally a solid substance.

Comment on solubility

Solubility of 2-(4-isobutyl-3-methyl-phenyl)sulfanylethanehydroxamic acid

The solubility of 2-(4-isobutyl-3-methyl-phenyl)sulfanylethanehydroxamic acid is influenced by several factors that are critical to understanding its behavior in various solvents. This compound, due to its complex structure, exhibits distinctive characteristics in solubility:

  • Polarity: The presence of hydroxamic acid functionality typically increases polarity, enhancing solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The amide and hydroxyl groups can participate in hydrogen bonding, further facilitating solubility in protic solvents.
  • Hydrophobic Effects: The isobutyl and methyl groups contribute to a hydrophobic character, which may limit solubility in non-polar solvents such as hexane or toluene.
  • Temperature Sensitivity: As with many organic compounds, solubility can vary with temperature; generally, solubility increases with an increase in temperature.

Overall, the solubility profile of 2-(4-isobutyl-3-methyl-phenyl)sulfanylethanehydroxamic acid is a balance between its polar and non-polar characteristics. Its solubility behavior can be summarized as:

  1. Good solubility in polar solvents.
  2. Limited solubility in non-polar solvents.
  3. Temperature-dependent solubility characteristics.

In conclusion, understanding the solubility of this compound is essential for its applications in various chemical processes and solvent systems.

Interesting facts

Interesting Facts About 2-(4-isobutyl-3-methyl-phenyl)sulfanylethanehydroxamic acid

2-(4-isobutyl-3-methyl-phenyl)sulfanylethanehydroxamic acid is a fascinating compound with numerous implications and potential applications in the field of chemistry and medicinal science. Here are some intriguing points to consider:

  • Biological Activity: This compound has garnered attention due to its potential role as an inhibitor in various biological pathways. Hydroxamic acids, in general, are known for their ability to chelate metal ions, which can influence enzymatic processes.
  • Drug Development: The unique structure of this compound may provide a scaffold for the development of novel pharmaceuticals. Its distinctive side chains, particularly the 4-isobutyl and 3-methyl groups, can enhance interactions with specific biological targets.
  • Research Opportunities: With ongoing investigations into nitric oxide synthase and matrix metalloproteinases, this compound could serve as a lead structure in the development of therapeutics for conditions such as cancer and cardiovascular diseases.
  • Structure-Activity Relationship: A deep dive into the structure-activity relationships (SAR) can yield vital insights into optimizing this compound for better efficacy and reduced toxicity. Tweaking the side chains can help in discovering more effective derivatives.
  • Environmental Science: Sulfanyl groups can often play a role in environmental chemistry, interacting with various metal ions in soil and water systems, showcasing the multi-disciplinary relevance of this compound.

In summary, the study of 2-(4-isobutyl-3-methyl-phenyl)sulfanylethanehydroxamic acid opens up exciting avenues in both biological and environmental research. As scientists continue to explore its properties and functions, there is no telling what innovative solutions it might bring to contemporary challenges!

Synonyms
BRN 2858225
ACETOHYDROXAMIC ACID, 2-(4-(ISOBUTYLTHIO)-m-TOLYL)-
DTXSID40165920
2-(4-(Isobutylthio)-m-tolyl)acetohydroxamic acid
15560-08-4
DTXCID5088411