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2-(4-isobutylphenyl)ethanehydroxamic acid

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Identification
Molecular formula
C12H17NO2
CAS number
.584771-47-5
IUPAC name
2-(4-isobutylphenyl)ethanehydroxamic acid
State
State

At room temperature, 2-(4-isobutylphenyl)ethanehydroxamic acid is a solid.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
409.00
Boiling point (Kelvin)
682.15
General information
Molecular weight
207.28g/mol
Molar mass
207.2810g/mol
Density
1.0100g/cm3
Appearence

2-(4-isobutylphenyl)ethanehydroxamic acid is typically a white to off-white crystalline solid.

Comment on solubility

Solubility of 2-(4-Isobutylphenyl)ethanehydroxamic Acid

The solubility of 2-(4-isobutylphenyl)ethanehydroxamic acid in various solvents is of significant interest in chemical research and applications. Understanding its solubility characteristics can aid in predicting its behavior in different environments. Here are some key points regarding its solubility:

  • Water Solubility: This compound has limited solubility in water due to its hydrophobic isobutyl group. The bulky non-polar characteristics may hinder its interaction with polar water molecules.
  • Organic Solvents: Solubility in organic solvents is expected to be higher, particularly in non-polar and polar aprotic solvents such as hexane, acetone, and DMSO.
  • pH Influence: The solubility may also be affected by pH, where the protonation state of the hydroxamic acid group can change, influencing its solubility profile.
  • Temperature Dependency: As with many compounds, solubility might increase with temperature, making it easier to dissolve in higher temperature conditions.

In summary, while 2-(4-isobutylphenyl)ethanehydroxamic acid tends to have limited solubility in water, its solubility can significantly improve in suitable organic solvents. The various factors influencing solubility emphasize the need for careful consideration in applications such as drug formulation or synthesis within chemical processes.

Interesting facts

Interesting Facts about 2-(4-isobutylphenyl)ethanehydroxamic acid

2-(4-isobutylphenyl)ethanehydroxamic acid is a fascinating compound with a variety of interesting properties and applications. Here are some key points to consider:

  • Hydroxamic Acids: This compound belongs to the hydroxamic acid family, which is known for containing a functional group that includes a hydroxylamine group attached to a carbonyl group. This unique structure aids in forming complexes with metal ions, making it useful in medicinal chemistry.
  • Metal Chelation: Hydroxamic acids, including this one, are often studied for their ability to chelate metals. This property is particularly important in the treatment of certain diseases and in the development of targeted therapies.
  • Biological Significance: Research indicates that compounds like 2-(4-isobutylphenyl)ethanehydroxamic acid may exhibit anti-tumor activities, making it a candidate for further investigations in cancer research.
  • Synthetic Pathways: The synthesis of this compound can involve various methods, often leveraging simple starting materials and well-established organic reactions, showcasing the creativity and versatility of organic chemistry.
  • Potential Applications: Beyond medicinal use, hydroxamic acids have applications in agriculture as herbicides and are being explored in the field of material science for their potential in creating novel polymers.

As a scientist or a chemistry student, it is exciting to delve into the intricacies of such compounds, understanding not just their structure but also their potential roles in multiple fields of study. “The boundaries of chemistry are only as limited as our curiosity and creativity,” could easily resonate with your explorations of compounds like 2-(4-isobutylphenyl)ethanehydroxamic acid!

Synonyms
2-(p-Isobutylphenyl)acetohydroxamic acid
BRN 1956776
ACETOHYDROXAMIC ACID, 2-(p-ISOBUTYLPHENYL)-
3347-48-6
DTXSID30187116
DTXCID40109607