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Ibuprofen

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Identification
Molecular formula
C13H18O2
CAS number
15687-27-1
IUPAC name
2-[4-(isopropylamino)phenyl]acetic acid
State
State

At room temperature, ibuprofen is typically a solid.

Melting point (Celsius)
76.00
Melting point (Kelvin)
349.00
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.00
General information
Molecular weight
206.28g/mol
Molar mass
206.2810g/mol
Density
1.0340g/cm3
Appearence

Ibuprofen is a white or off-white crystalline powder that may have a slight characteristic odor. It may also appear as white crystals. The compound is often utilized in the form of tablets, capsules, or liquid suspensions when used in medications.

Comment on solubility

Solubility of 2-[4-(isopropylamino)phenyl]acetic acid

The solubility of 2-[4-(isopropylamino)phenyl]acetic acid, a compound with both polar and non-polar characteristics, can be intriguing. This compound typically exhibits varying solubility in different solvents due to its structural components. Here are some key points regarding its solubility:

  • Polar Solvents: Generally, compounds with carboxylic acid groups, such as 2-[4-(isopropylamino)phenyl]acetic acid, tend to be more soluble in polar solvents like water and ethanol because of hydrogen bonding interactions.
  • Non-Polar Solvents: The isopropyl group introduces hydrophobic characteristics, leading to lower solubility in non-polar solvents such as hexane or chloroform.
  • pH Influence: The solubility can also be influenced by the pH of the solution. In acidic conditions, the carboxylic group may remain protonated, reducing solubility, while in basic conditions, it can deprotonate, enhancing solubility.

In summary, the solubility of 2-[4-(isopropylamino)phenyl]acetic acid is a multifaceted aspect that can significantly impact its chemical behavior and applications. As noted, the interaction with solvents is largely dictated by its functional groups and the overall molecular structure, making understanding its solubility crucial for practical use.

Interesting facts

Interesting Facts About 2-[4-(isopropylamino)phenyl]acetic Acid

2-[4-(isopropylamino)phenyl]acetic acid, also known as a member of the amino acid derivatives, serves a significant role in biochemical research and pharmaceutical applications. Here are some fascinating insights:

  • Pharmacological Relevance: This compound is often studied for its potential use as an anti-inflammatory and analgesic agent. It may have therapeutic applications that target pain relief while minimizing side effects.
  • Structural Intrigue: The unique structure, featuring an isopropylamino group, contributes to its pharmacokinetic properties, influencing how the compound interacts with biological systems.
  • Derivative Chemistry: It serves as a foundational structure for synthesizing other bioactive compounds, showcasing how small modifications can lead to significant changes in biological activity.
  • Research Applications: The compound is often utilized in laboratory settings for studying protein interactions and enzymatic processes, aiding in understanding complex biological mechanisms.
  • Market Interest: Due to its chemical properties, there is ongoing interest in developing derivatives and analogs of this compound in the drug discovery process, reflecting its importance in medicinal chemistry.

In summary, 2-[4-(isopropylamino)phenyl]acetic acid exemplifies the intersection of chemistry and medicine, making it a noteworthy subject for both academic research and practical applications in the pharmaceutical industry. Its ongoing study continues to inspire advancements in drug development and therapeutic solutions.

Synonyms
(4-Isopropylaminophenyl)acetic acid
ACETIC ACID, 2-(p-(ISOPROPYLAMINO)PHENYL)-
BRN 2364441
4-((1-Methylethyl)amino)benzeneacetic acid
Acide isopropylamino-4 phenylacetique [French]
Acide isopropylamino-4 phenylacetique
DTXSID50182168
Benzeneacetic acid, 4-((1-methylethyl)amino)-
4-[(1-Methylethyl)amino]benzeneacetic acid
RefChem:316506
DTXCID60104659
Benzeneacetic acid, 4-((1-methylethyl)amino)-(9CI)
27864-26-2
SCHEMBL9911354
AKOS017517986