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Trimethoxyphenylethylpiperazine

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Identification
Molecular formula
C21H28N2O4
CAS number
67469-78-5
IUPAC name
2-[4-(m-tolylmethyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)ethanone
State
State

At room temperature, this compound is a solid.

Melting point (Celsius)
79.00
Melting point (Kelvin)
352.20
Boiling point (Celsius)
525.40
Boiling point (Kelvin)
798.60
General information
Molecular weight
372.48g/mol
Molar mass
372.4750g/mol
Density
1.1960g/cm3
Appearence

Trimethoxyphenylethylpiperazine typically appears as a white or off-white crystalline solid. This compound can also present itself in powdered form. It is generally not hygroscopic and is stable when kept in dry, airtight conditions.

Comment on solubility

Solubility of 2-[4-(m-tolylmethyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)ethanone

The solubility of 2-[4-(m-tolylmethyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)ethanone is influenced by its complex molecular structure. Generally, the solubility of organic compounds can be characterized based on the following factors:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents like water.
  • Hydrophobic Regions: Non-polar sections tend to prefer non-polar solvents, which can reduce solubility in polar environments.
  • Molecular Weight: Higher molecular weight typically leads to lower solubility due to increased intermolecular forces.

In the case of this compound, the combination of the piperazine moiety and the multiple methoxy groups suggests that it may exhibit:

  • Moderate solubility in polar solvents, particularly due to the ether linkages in the methoxy groups.
  • Lower solubility in non-polar solvents, considering the presence of bulky aromatic groups.

As a general rule of thumb, compounds with large and complex structures, such as this one, often show variable solubility depending on the solvent used. It could be summarized by stating, *"Solubility is a function of both structure and environment."* Therefore, empirical testing is recommended to ascertain the exact solubility profile in various solvents.

Interesting facts

Exploring 2-[4-(m-tolylmethyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)ethanone

This intriguing compound, known for its unique structural characteristics, belongs to a class of molecules that have garnered interest in pharmacological studies. Here are some captivating insights into this compound:

  • Diverse Applications: Due to its piperazine core, this compound has the potential to exhibit a range of biological activities, making it a subject of research in drug development.
  • Structural Complexity: The presence of multiple functional groups, including methoxy and piperazine, hints at complex interactions with biological targets.
  • Potential Therapeutic Use: Compounds with similar structures have been investigated for their efficacy in treating various conditions, including psychiatric disorders and as antidepressants.
  • Chemical Synthesis: Understanding the synthesis pathways of such compounds not only aids in practical applications but also deepens insights into reaction mechanisms in organic chemistry.
  • Research Significance: Ongoing studies may unveil new properties that could contribute to advancements in medicinal chemistry and therapeutic strategies.

As a scientist or a student diving into the fascinating world of organic compounds, it is essential to appreciate how subtle changes in molecular structure can lead to significant variations in biological activity and therapeutic potential. As such, this compound serves as a prime example of the diverse and often surprising nature of chemical compounds in today’s research landscape.