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4-Methoxytryptamine

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Identification
Molecular formula
C11H14N2O
CAS number
487-58-1
IUPAC name
2-(4-methoxy-1H-indol-3-yl)ethanamine
State
State

At room temperature, 4-methoxytryptamine is in a solid state. It is stable under standard conditions of temperature and pressure, presenting as a crystalline powder.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
347.60
Boiling point (Kelvin)
620.75
General information
Molecular weight
190.25g/mol
Molar mass
190.2450g/mol
Density
1.2280g/cm3
Appearence

4-Methoxytryptamine is typically a white to yellowish crystalline solid. It is commonly encountered in the form of an odorless powder. Its crystalline structure contributes to its somewhat granular feel when handled.

Comment on solubility

Solubility of 2-(4-methoxy-1H-indol-3-yl)ethanamine

The solubility of 2-(4-methoxy-1H-indol-3-yl)ethanamine can offer intriguing insights into its chemical behavior and potential applications. This compound, known for its unique structure, exhibits distinct solubility characteristics that are influenced by various factors.

Key Aspects of Solubility:

  • Solvent Interactions: The presence of the methoxy group can enhance solubility in polar solvents due to its ability to participate in hydrogen bonding.
  • Hydrophobic Regions: The indole moiety contributes to hydrophobic interactions, which may hinder solubility in aqueous environments.
  • pH Dependence: The solubility may vary significantly with pH changes, affecting the ionization state of the amine group.
  • Temperature Effects: Increasing temperature generally leads to higher solubility for many organic compounds; however, this can vary depending on specific interactions within the structure.

Due to these factors, the solubility of 2-(4-methoxy-1H-indol-3-yl)ethanamine is often described as moderate to high in organic solvents and limited in water. Understanding these solubility dynamics is crucial for utilizing this compound effectively in various chemical applications.

Interesting facts

Interesting Facts about 2-(4-methoxy-1H-indol-3-yl)ethanamine

2-(4-methoxy-1H-indol-3-yl)ethanamine, often referred to as a derivative of the indole structure, has captured the attention of chemists and pharmacologists alike due to its multifaceted biological properties.

Biological Significance

  • It serves as a significant precursor in the synthesis of various pharmaceuticals, showcasing its potential in medicinal chemistry.
  • This compound is studied for its interaction with neurotransmitter systems, suggesting roles in mood regulation and neuroprotection.
  • Research has indicated its potential as an antitumor agent, adding to its therapeutic prospects in oncology.

Chemical Characteristics

One of the fascinating aspects of 2-(4-methoxy-1H-indol-3-yl)ethanamine is its structural intricacy:

  • The indole ring—a core structure in many biologically active compounds—provides a rich landscape for chemical reactivity.
  • The addition of a methoxy group enhances its lipophilicity, which can influence the compound's absorption and distribution within biological systems.

Research and Applications

Ongoing research projects are exploring the compound’s potential in various domains:

  • It is being investigated in the context of neuroscience for its possible effects on serotonin receptors.
  • Studies are examining its utility in synthetic pathways for developing new antidepressants.
  • The compound's properties may also open doors to innovative treatments in areas like neurodegenerative diseases.

Overall, 2-(4-methoxy-1H-indol-3-yl)ethanamine stands out as a remarkable compound that bridges the interface of organic chemistry and pharmacology, making it a compelling subject of study for anyone keen on understanding the nuances of chemical compounds and their wide-ranging impacts on health and medicine.

Synonyms
3610-35-3
1H-Indole-3-ethanamine, 4-methoxy-
2-(4-methoxy-1H-indol-3-yl)ethan-1-amine
4-Methoxy-1H-indole-3-ethanamine
DTXSID70189679
DTXCID80112170
835-755-2
4-Methoxytryptamine
2-(4-methoxy-1H-indol-3-yl)ethanamine
CHEMBL343529
SCHEMBL1460696
WMBARRJMPVVQEZ-UHFFFAOYSA-N
DAA61035
BDBM50025223
MFCD03848075
AKOS006278394
AS-41707
CS-0107096
EN300-127766