Skip to main content

Fluoxetine

ADVERTISEMENT
Identification
Molecular formula
C17H26N2O3
CAS number
54910-89-3
IUPAC name
2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)-N-(2-pyrrolidin-1-ylethyl)acetamide
State
State

At room temperature, Fluoxetine is a solid. It is generally supplied in the form of a stable crystalline compound and is not volatilized under standard room conditions.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.00
Boiling point (Celsius)
535.70
Boiling point (Kelvin)
808.90
General information
Molecular weight
309.36g/mol
Molar mass
309.3640g/mol
Density
1.3000g/cm3
Appearence

Fluoxetine is typically found as a white to off-white crystalline solid. It may appear as a granular powder with no distinct odor. Its crystalline nature can give it a slightly shiny or lustrous appearance under certain lighting conditions.

Comment on solubility

Solubility of 2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)-N-(2-pyrrolidin-1-ylethyl)acetamide

The solubility of 2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)-N-(2-pyrrolidin-1-ylethyl)acetamide is influenced by its unique chemical structure, which includes both polar and non-polar features. This amphiphilic nature can yield interesting solubility characteristics:

  • Polar Interactions: The presence of the methoxy (-OCH3) groups contributes to polar interactions. This may enhance solubility in polar solvents such as water and alcohols.
  • Non-Polar Interactions: The aromatic rings within the compound introduce hydrophobic regions. These sections may hinder solubility in strictly polar solvents, making the compound more soluble in non-polar solvents such as chloroform or ether.
  • Influence of Temperature: Like many organic compounds, solubility can be temperature-dependent. Increased temperature generally increases solubility in liquid solvents, but this varies based on the solvent type.
  • pH Sensitivity: The solubility might also be affected by the pH of the solution, as protonation or deprotonation can alter the charge and solvation properties of the compound.

As a result, understanding solubility is crucial for applications involving 2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)-N-(2-pyrrolidin-1-ylethyl)acetamide, particularly in pharmacological contexts where solubility can influence biological activity and absorption.

Interesting facts

Interesting Facts about 2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)-N-(2-pyrrolidin-1-ylethyl)acetamide

This intriguing compound has garnered attention in the field of medicinal chemistry. Here are some captivating points:

  • Functionality: The unique structure of this compound, featuring both acetamide and ether linkages, makes it a great candidate for various biological evaluations, particularly in the realm of drug design.
  • Pharmacophore: Its framework may serve as a pharmacophore, enabling the exploration of interactions with biological targets, which can inspire the development of new therapeutic agents.
  • Bioavailability: The presence of the pyrrolidine moiety plays an important role in enhancing solubility and membrane permeability, potentially increasing the compound's bioavailability. As molecular design emphasizes these characteristics, this compound is of heightened interest.
  • Structure-Activity Relationship: Scientists often study variations of this compound to understand the correlation between its chemical structure and biological activity, providing valuable insights for optimization in future compounds.
  • Research Potential: Given its complex structure, this compound is an exciting subject for ongoing research in neuropharmacology and other related areas, where it could pave the way for breakthroughs in treating mental health disorders.

In conclusion, 2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)-N-(2-pyrrolidin-1-ylethyl)acetamide is more than just a complex chemical; it represents the exciting intersection of chemistry, biology, and medicine. As researchers continue to explore its properties and applications, the potential benefits for future therapeutic developments remain promising.