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Fenoprofen

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Identification
Molecular formula
C11H14O3
CAS number
31879-05-7
IUPAC name
2-(4-methoxyphenyl)butanoic acid
State
State

At room temperature, fenoprofen is in a solid state, typically marketed as capsules or tablets when used in pharmaceuticals.

Melting point (Celsius)
114.50
Melting point (Kelvin)
387.65
Boiling point (Celsius)
369.30
Boiling point (Kelvin)
642.45
General information
Molecular weight
244.29g/mol
Molar mass
244.2900g/mol
Density
1.1890g/cm3
Appearence

Fenoprofen is generally found as a white crystalline powder. It is practically insoluble in water but soluble in alcohol, chloroform, and ether, allowing it to be used in various pharmaceutical preparations.

Comment on solubility

Solubility of 2-(4-methoxyphenyl)butanoic acid

2-(4-methoxyphenyl)butanoic acid, often referred to for its unique structure, showcases varying solubility characteristics that make it a subject of interest in chemical studies. The solubility of this compound can be influenced by several factors:

  • Polar vs. Nonpolar solvents: Due to the presence of both polar (the carboxylic acid group) and nonpolar (the butyl and methoxy aromatic group) parts in its molecular structure, this compound tends to have moderate solubility in polar solvents, such as water, as well as in organic solvents.
  • Temperature dependence: Like many organic acids, the solubility of 2-(4-methoxyphenyl)butanoic acid generally increases with temperature. Higher temperatures can enhance the solvation process, thereby allowing for greater dissolution.
  • pH influence: The solubility of the compound is also dependent on the pH of the solution. In acidic environments, its solubility may decrease as the non-ionized form predominates, whereas in basic conditions, it tends to dissolve more readily due to deprotonation.

As a result, when evaluating the solubility of 2-(4-methoxyphenyl)butanoic acid, it’s essential to consider these underlying factors. Understanding its solubility behavior not only aids in practical applications but also serves to deepen knowledge in organic chemistry.

Interesting facts

Interesting Facts about 2-(4-methoxyphenyl)butanoic acid

2-(4-methoxyphenyl)butanoic acid, also known as a member of the phenylbutanoic acids, exhibits a rich interplay of chemical properties and biological activity. This compound has garnered attention within various fields due to its unique structure and potential applications.

Structural Insights

The compound features a butanoic acid moiety attached to a methoxy-substituted phenyl ring, making it an intriguing subject for study. Its structural formulation allows for various interactions, which can influence its reactivity and biological function.

Potential Applications

  • Pharmaceutical Research: The presence of the methoxy group can enhance the pharmacokinetics of drugs, potentially leading to increased efficacy.
  • Biological Activity: Compounds like 2-(4-methoxyphenyl)butanoic acid may show anti-inflammatory properties, making them valuable in developing treatments for conditions like arthritis.
  • Research Tool: As a synthetic intermediate, this compound facilitates the study of larger, complex molecules in chemical biology.

Historical Relevance

Compounds of this nature have been studied for decades, often in the context of their derivatives or analogs. The study of phenylbutanoic acids has led to significant advancements in medicinal chemistry, highlighting the importance of structure-activity relationships in drug design.

Quote to Reflect On

"In every molecule lies a story; the more we understand the individual components, the closer we get to uncovering new realms of science."

In summary, 2-(4-methoxyphenyl)butanoic acid stands as a testament to the intricate connections between structure and function in chemistry. Its exploration opens up avenues for potential breakthroughs in therapeutic developments and further understanding of molecular behavior.

Synonyms
2-(4-methoxyphenyl)butanoic acid
DTXSID20952113
RefChem:457972
DTXCID801380213
820-909-3
29644-99-3
MFCD00156920
(R/S)-2-(4-METHOXY-PHENYL)-BUTYRIC ACID
2-(p-Methoxyphenyl)butyric acid
BRN 3261305
BUTYRIC ACID, 2-(p-METHOXYPHENYL)-
2-(4-methoxyphenyl)butanoicacid
NSC617282
p-methoxyphenylbutyric acid
4-methoxyphenylbutanoic acid
SCHEMBL1587133
CHEMBL1973358
SHXBXUJGKPPUOS-UHFFFAOYSA-N
2-(4'-methoxyphenyl)butyric acid
EBA64499
AKOS005255920
NSC-617282
KS-10940
NCI60_005194
SY143040
EN300-106620
G41682
Z792377198