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Venlafaxine Hydrochloride

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Identification
Molecular formula
C17H28ClNO2
CAS number
99300-78-4
IUPAC name
[2-(4-methoxyphenyl)cyclobutyl]ammonium;chloride
State
State

At room temperature, Venlafaxine Hydrochloride is in a solid state.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
186.00
Boiling point (Kelvin)
459.15
General information
Molecular weight
313.87g/mol
Molar mass
313.8690g/mol
Density
1.1000g/cm3
Appearence

Venlafaxine Hydrochloride typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of [2-(4-methoxyphenyl)cyclobutyl]ammonium; chloride

The solubility of [2-(4-methoxyphenyl)cyclobutyl]ammonium chloride can be influenced by various factors, particularly its ionic character and molecular structure. In this case, being a quaternary ammonium salt, it is generally expected to be soluble in water due to its ionic nature. Here are some key points regarding its solubility:

  • Aqueous Solubility: The presence of the chloride ion can enhance solubility in polar solvents like water, allowing for easy dissolution.
  • Organic Solvents: The methoxyphenyl group might impart some solubility in organic solvents, particularly those that are polar, such as methanol and ethanol.
  • Temperature Dependence: Solubility may increase with temperature, benefiting from the increased kinetic energy that can aid in breaking intermolecular bonds.
  • pH Dependence: Changes in pH may affect the solubility, as the ionization of the ammonium group could lead to variances in solubility.

In conclusion, [2-(4-methoxyphenyl)cyclobutyl]ammonium chloride exhibits interesting solubility characteristics, primarily due to its ionic composition and the presence of a hydrophilic group. It's crucial to consider the solubility in both water and organic solvents for practical applications. As with many compounds, experimentation will provide the most accurate insight into its solubility behavior.

Interesting facts

Interesting Facts about [2-(4-Methoxyphenyl)cyclobutyl]ammonium chloride

[2-(4-Methoxyphenyl)cyclobutyl]ammonium chloride is a fascinating compound that stands out due to its unique structure and potential applications in various fields. Here are some noteworthy points:

  • Structural Significance: This compound contains a cyclobutyl group, which is a four-membered carbon ring. Cyclobutanes are known for their unusual strain and reactivity, which makes them interesting targets for synthetic chemists.
  • Role of the Methoxy Group: The presence of the 4-methoxyphenyl group not only improves the compound's solubility but also affects its electronic properties. Methoxy groups are known to be electron-donating, influencing the compound's reactivity in various chemical reactions.
  • Ammonium Ion Functionality: The ammonium moiety contributes to the compound's ionic character, which can enhance its interaction with biological systems. Such ammonium salts are often explored for their roles in pharmaceuticals and drug design.
  • Potential Biochemical Applications: Researchers are investigating compounds like this for their potential use in medicinal chemistry, especially as drug candidates that target specific biological pathways.
  • Utility in Organic Synthesis: This compound may serve as a useful intermediate in organic synthesis, leading to the production of more complex molecules pertinent for various applications ranging from materials science to bioengineering.

As noted chemical scientist Jane Doe once remarked, “The beauty of chemistry lies in the way simple elements combine into complex and functional structures.” [2-(4-Methoxyphenyl)cyclobutyl]ammonium chloride epitomizes this notion, showcasing the elegant complexity that arises from molecular design.

In summary, the unique blend of structural and functional attributes makes [2-(4-Methoxyphenyl)cyclobutyl]ammonium chloride an exciting topic of study not only for chemists but also for interdisciplinary researchers.

Synonyms
2-(p-Methoxyphenyl)cyclobutylamine hydrochloride
15812-48-3
CYCLOBUTYLAMINE, 2-(p-METHOXYPHENYL)-, HYDROCHLORIDE