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Identification
Molecular formula
C9H13NO4S
CAS number
nil
IUPAC name
2-[(4-methoxyphenyl)sulfonyl-(3-pyridylmethyl)amino]-3-methyl-benzenecarbohydroxamic acid
State
State

At room temperature, the compound is a solid, generally manageable in dry conditions but sensitive to moisture, which can cause clumping. It should be handled in a well-ventilated space to avoid inhalation of dust particles.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
465.00
Boiling point (Kelvin)
738.15
General information
Molecular weight
370.42g/mol
Molar mass
370.4200g/mol
Density
1.3000g/cm3
Appearence

The compound is typically a crystalline solid, showing a fine powder form which may range in color from off-white to light tan or brown, dependent on purity and specific sample characteristics.

Comment on solubility

Solubility of 2-[(4-methoxyphenyl)sulfonyl-(3-pyridylmethyl)amino]-3-methyl-benzenecarbohydroxamic acid (C9H13NO4S)

The solubility of compounds can greatly influence their practical applications, and this specific compound presents interesting characteristics in this regard. Here are some key points to consider:

  • Polarity: The presence of multiple functional groups, such as the hydroxamic acid and sulfonyl moieties, typically increases the polarity of the molecule, which often enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxamic acid's -OH group can participate in hydrogen bonding, a factor that may further improve its solubility in aqueous environments. As a general rule, compounds that can form hydrogen bonds are more likely to dissolve in polar solvents.
  • Solvent Interaction: This compound may exhibit varying solubility in organic solvents. Non-polar solvents may not solvate the compound effectively due to its polar characteristics.
  • Temperature Dependence: Solubility can be influenced by temperature; this compound may show increased solubility with a rise in temperature.

In conclusion, while predicting the exact solubility without experimental data is challenging, one can reasonably speculate that the structural features of 2-[(4-methoxyphenyl)sulfonyl-(3-pyridylmethyl)amino]-3-methyl-benzenecarbohydroxamic acid suggest good solubility in polar solvents. As the adage goes, "like dissolves like", which often rings true in the world of chemistry.

Interesting facts

Interesting Facts about 2-[(4-methoxyphenyl)sulfonyl-(3-pyridylmethyl)amino]-3-methyl-benzenecarbohydroxamic acid

This compound is a fascinating example of a hydroxamic acid, which plays a significant role in medicinal chemistry. Hydroxamic acids are known for their ability to form complexes with metal ions, making them important in the development of metalloproteinase inhibitors. Here are some key points to consider:

  • Complexation Properties: The hydroxamic acid functional group allows for strong interactions with transition metals, potentially influencing various biological processes.
  • Therapeutic Potential: Compounds derived from hydroxamic acid have been investigated for their therapeutic potential in conditions like cancer, where they inhibit matrix metalloproteinases (MMPs).
  • Structure Activity Relationship (SAR): The specific substituents on this compound, such as the 4-methoxyphenyl and 3-pyridylmethyl groups, can greatly affect its biological activity and selectivity, making it a subject of interest in drug design.

Moreover, this compound demonstrates the complexity and versatility of organic chemistry. Its multiple functional groups and the potential for diverse interactions in biological systems illustrate the intricate balance between structure and activity. Developing such compounds requires a keen understanding of both chemical properties and biological mechanisms.

In the words of scientists, "The beauty of organic compounds lies in their ability to evolve and adapt within biological frameworks." This compound serves as a testament to that philosophy, bridging the gap between chemistry and pharmacology.

Synonyms
WAY-151693
n-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide
WAY 151693
CHEMBL70176
N-hydroxy-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]-3-methylbenzamide
206551-25-9
1fls
N-Hydroxy-2-{[(4-methoxyphenyl)sulfonyl](3-pyridinylmethyl)amino}-3-methylbenzamide
N-hydroxy-3-methyl-2-[N-(pyridin-3-ylmethyl)4-methoxybenzenesulfonamido]benzamide
WAY
N-Hydroxy-2-(((4-methoxyphenyl)sulfonyl)(3-pyridinylmethyl)amino)-3-methylbenzamide
N-hydroxy-3-methyl-2-(N-(pyridin-3-ylmethyl)4-methoxybenzenesulfonamido)benzamide
SCHEMBL6129930
BDBM50096463
WAY151693
DB02071
NS00068369
Q27093149
N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-3-methylbenzamide
N-hydroxy-2-{[(4-methoxyphenyl)sulfonyl](pyridin-3-ylmethyl)amino}-3-methylbenzamide