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Flufenamic acid

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Identification
Molecular formula
C15H10F3NO3
CAS number
530-78-9
IUPAC name
2-[4-methyl-2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]acetic acid
State
State

At room temperature, flufenamic acid is typically in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
463.40
Boiling point (Kelvin)
736.60
General information
Molecular weight
281.24g/mol
Molar mass
281.2370g/mol
Density
1.4165g/cm3
Appearence

Flufenamic acid appears as a white to slightly yellow crystalline powder. It may vary slightly in color depending on purity and processing.

Comment on solubility

Solubility of 2-[4-methyl-2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]acetic acid

The solubility of 2-[4-methyl-2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]acetic acid can be influenced by various factors, including its chemical structure and the solvent used.

Key Factors Influencing Solubility:

  • Polarity: The presence of polar functional groups, such as carboxylic acids, generally increases solubility in polar solvents.
  • Hydrogen Bonding: This compound has multiple sites for potential hydrogen bonding, enhancing its solubility in protic solvents like water.
  • Temperature: Higher temperatures often improve solubility for many organic compounds, affecting the dissolution rate and equilibrium.
  • pH Levels: As a weak acid, the solubility of this compound increases in basic conditions due to deprotonation, which improves its ability to dissolve.

In summary, while 2-[4-methyl-2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]acetic acid likely presents reasonable solubility in water due to its polar characteristics, considering the specific application and the solvent environment is essential for optimal results.

Ultimately, understanding the solubility of chemical compounds, such as this one, is crucial for various applications, from drug formulation to environmental science. Always bear in mind:

  • Solubility is not a fixed property; it varies with changes in the formulation and conditions.
  • Conducting experiments to determine solubility in practical scenarios is vital.
Interesting facts

Interesting Facts about 2-[4-methyl-2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]acetic acid

2-[4-methyl-2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]acetic acid, often referred to in shorthand, boasts a fascinating chemical profile that intrigues both researchers and students alike. This compound is particularly noted for its versatile applications and unique structural components. Here are some interesting aspects:

  • Biological Significance: This compound is explored for its potential role in various therapeutic contexts, primarily as a pharmaceutical intermediate. Many compounds of similar structure are key players in drug development, which can lead to innovative treatments.
  • Fluorinated Phenyl Group: The presence of the trifluoromethyl group is notable. This feature significantly enhances the compound's lipophilicity, making it more effective in penetrating biological membranes, which can be crucial for its performance in medicinal chemistry.
  • Solubility Dynamics: The different functional groups present in this compound contribute to its physicochemical properties, influencing solubility and interaction with biological targets. Such characteristics can parameterize its bioavailability and efficacy in various applications.
  • Research Potential: Ongoing research into 2-[4-methyl-2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]acetic acid explores synthetic pathways and applications, reflecting the compound's growing significance in contemporary chemistry.
  • Multi-functional Utilization: Beyond pharmacology, the unique structure lends itself to exploration in fields such as agrochemicals, where similar compounds are used to enhance crop productivity and protect against pests.

This compound illustrates the complexity and beauty of organic chemistry. As researchers dive deeper, they may unveil even more exciting properties and applications, showcasing the importance of these intricate molecular designs in both science and industry.

Synonyms
BRN 2400001
ACETIC ACID, ((2-(alpha,alpha,alpha-TRIFLUORO-m-TOLUAMIDO)-p-TOLYL)OXY)-
6238-85-3
((2-(m-(Trifluoromethyl)benzamido)-p-tolyl)oxy)acetic acid
DTXSID40211436
DTXCID40133927