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Phenylbutazone

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Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
2-[(4-methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide
State
State

At room temperature, phenylbutazone is a solid. It is usually found in pharmaceutical laboratories and is administered in tablet form for medical use.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
308.34g/mol
Molar mass
308.3360g/mol
Density
1.2650g/cm3
Appearence

Phenylbutazone typically appears as a white or off-white crystalline powder. It is odorless and has a slightly bitter taste. The substance is often used in pharmaceutical formulations, primarily as an anti-inflammatory medication.

Comment on solubility

Solubility of 2-[(4-methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide

The solubility of 2-[(4-methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide can be influenced by several factors related to its chemical structure. Here are some noteworthy insights:

  • Polarity: Given the presence of nitro and hydrazone functional groups, which are polar in nature, this compound may exhibit moderate solubility in polar solvents such as water or methanol.
  • Hydrophobic Regions: The presence of a phenyl group suggests that there are also hydrophobic regions within the molecule, which could lead to decreased solubility in non-polar solvents.
  • Temperature Dependency: Like many organic compounds, its solubility may increase with temperature, allowing for better interaction with solvent molecules.
  • pH Sensitivity: The solubility could also be affected by the pH of the solution, as functional groups may ionize and increase solubility at different pH levels.

Ultimately, the solubility of 2-[(4-methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide is a complex interplay of its structural characteristics and the solvent environment. As such, empirical testing is often necessary to determine its exact solubility in various solvents.

Interesting facts

Interesting Facts about 2-[(4-methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide

This intriguing compound, known as 2-[(4-methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide, belongs to a class of compounds called hydrazones, which are often recognized for their unique structural and functional aspects. Here are some fascinating insights into this compound:

  • Biological Relevance: Many hydrazones showcase fascinating biological activities, including anti-inflammatory and antimicrobial properties. This suggests that derivatives of this compound could hold promise in pharmaceutical applications.
  • Chemical Transformations: Hydrazones are known to participate in various chemical reactions such as cyclization and oxidation, making them valuable intermediates in organic synthesis.
  • Stability Factors: The presence of the nitro group in the phenyl moiety can enhance the compound's stability and reactivity, impacting how it may interact with other molecules in biochemical pathways.
  • Structure-Activity Relationship (SAR): Researchers often explore the influence of structural modifications on the biological efficacy of compounds. Hence, the different substituents in this compound may dictate its activity and potential therapeutic benefits.
  • Colorimetric Applications: Some hydrazone compounds exhibit colorimetric properties that can be exploited in analytical chemistry for qualitative and quantitative analysis.

In the realm of synthetic organic chemistry, understanding the properties and behaviors of such compounds can lead to the discovery of new materials and drugs, reinforcing the importance of studying molecules like 2-[(4-methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide. As a scientist delves into its potential, the journey of exploration continues, revealing the wonders encapsulated within its structure.