4-nitrophenyl-(4-methylpiperazin-1-yl)ethanone

Identification

Molecular formula

C₁₃H₁₆N₄O₃

CAS number

24939-25-1

IUPAC name

2-(4-methylpiperazin-1-yl)imino-1-(4-nitrophenyl)ethanone

State

At room temperature, this compound is generally found in a solid state. It is relatively stable under standard conditions but should be stored in a cool, dry place away from light to prevent degradation.

Melting point (Celsius)

225.50

Melting point (Kelvin)

498.70

Boiling point (Celsius)

415.60

Boiling point (Kelvin)

688.80

General information

Molecular weight

290.31g/mol

Molar mass

290.3120g/mol

Density

1.2645g/cm³

Appearence

This compound appears as a yellow to orange crystalline powder with a distinct aromatic odor. It may vary slightly in shade depending on purity and the presence of impurities.

Comment on solubility

Solubility of 2-(4-methylpiperazin-1-yl)imino-1-(4-nitrophenyl)ethanone

The solubility of the compound 2-(4-methylpiperazin-1-yl)imino-1-(4-nitrophenyl)ethanone can be influenced by several factors, given its complex structure, which includes both a piperazine ring and a nitrophenyl group. Here are some insights into its solubility characteristics:

Polarity: The presence of the nitro group (–NO₂) introduces polarity, which may enhance solubility in polar solvents like water.
Hydrogen Bonding: The piperazine moiety can engage in hydrogen bonding, potentially increasing solubility in polar solvents.
Solvent Considerations: It is expected to be more soluble in organic solvents such as methanol or ethanol compared to non-polar solvents due to its functional groups.
pH Dependency: The solubility might change with pH alterations, as the piperazine group could become protonated, affecting its solubility profile.

To summarize, while solubility can vary widely based on environment, it is likely that 2-(4-methylpiperazin-1-yl)imino-1-(4-nitrophenyl)ethanone shows moderate to good solubility in polar solvents, leveraging its polar and hydrogen-bond-capable functional groups.

Interesting facts

Interesting Facts about 2-(4-methylpiperazin-1-yl)imino-1-(4-nitrophenyl)ethanone

2-(4-methylpiperazin-1-yl)imino-1-(4-nitrophenyl)ethanone is a fascinating compound that finds relevance in various fields of chemistry and pharmaceuticals. Known for its unique structure, this compound presents numerous interesting characteristics:

Pharmaceutical Relevance: Compounds similar to this one are often investigated for their potential as drug candidates, especially in the field of antidepressants and antitumor agents.
Structural Complexity: The combination of a piperazine ring and nitrophenyl group creates a molecule with significant steric and electronic properties, making it a subject of interest for medicinal chemistry research.
Synthetic Pathways: The synthesis of this compound can involve various methods like iterative coupling reactions, showcasing the versatility of organic synthesis techniques.
Biological Activity: Preliminary studies indicate that compounds of this nature can exhibit modulatory effects on various biological pathways, inspiring further investigation into their mechanisms of action.

As a chemist or a student of chemistry, understanding the properties and potential applications of such compounds is crucial not only for academic purposes but also for breaking grounds in new drug developments. Indeed, "the future of medicinal chemistry lies in the comprehensively understanding the relationships between structure and activity.”

This compound serves as a prime example of how complex organic molecules can lead to groundbreaking discoveries, thanks to their diverse functionalities and applications in science.