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Loperamide hydrochloride

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Identification
Molecular formula
C29H34ClN3O2S
CAS number
34552-83-5
IUPAC name
2-(4-methylpiperazin-4-ium-1-yl)imino-1-(4-phenylsulfanylphenyl)ethanone;chloride
State
State

State: Loperamide hydrochloride is a solid at room temperature, typically forming a crystalline powder.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
513.09g/mol
Molar mass
513.0490g/mol
Density
1.2600g/cm3
Appearence

Loperamide hydrochloride is a white or almost white crystalline powder. It is generally solid at room temperature and shows no color.

Comment on solubility

Solubility of 2-(4-methylpiperazin-4-ium-1-yl)imino-1-(4-phenylsulfanylphenyl)ethanone; chloride

The solubility of the compound 2-(4-methylpiperazin-4-ium-1-yl)imino-1-(4-phenylsulfanylphenyl)ethanone; chloride can be influenced by several factors. Understanding its solubility characteristics is essential for practical applications. Here are some considerations:

  • Solvent Nature: The solubility can vary significantly in different solvents. Polar solvents such as water may improve the solubility of this ionic compound due to favorable interactions.
  • pH Sensitivity: The presence of the piperazine group indicates the potential for protonation, which may enhance solubility in acidic conditions.
  • Temperature Effects: Generally, increasing temperature can increase solubility for many compounds, but the specific behavior should be empirically determined.
  • Crystallinity: The degree of crystallinity can affect how soluble the compound is; less crystalline forms may dissolve more readily.

In summary, the solubility of 2-(4-methylpiperazin-4-ium-1-yl)imino-1-(4-phenylsulfanylphenyl)ethanone; chloride can be described as:

  1. Potentially high in polar solvents.
  2. Variable with changes in pH.
  3. Affected by temperature and crystallinity.

In light of these factors, specific solubility data should be obtained through experimentation to determine optimal conditions for use.

Interesting facts

Interesting Facts about 2-(4-Methylpiperazin-4-ium-1-yl)imino-1-(4-phenylsulfanylphenyl)ethanone; chloride

This intriguing compound showcases a fascinating blend of organic and medicinal chemistry. Its unique structural features and functional groups present numerous avenues for exploration in both theoretical and applied contexts. Here are some compelling aspects of this compound:

  • Complex Structure: The presence of both a piperazine ring and a phenylsulfanyl group indicates potential for diverse reactivity and applications in drug development.
  • Pharmacological Interest: Compounds containing piperazine moieties are known to exhibit a wide range of biological activities, including antipsychotic, antidepressant, and anticonvulsant properties.
  • Heterocyclic Chemistry: The incorporation of nitrogen in the heterocyclic framework enhances the compound's ability to participate in intermolecular interactions, making it a valuable candidate for receptor binding studies.
  • Potential Applications: Research into compounds like this one may offer insights into new therapeutic agents in treating neurological disorders, as well as other diseases impacted by neurotransmitter systems.

As a scientist or student of chemistry, you might find it fascinating that such compounds can act as molecular scaffolds for designing new drugs that target specific biological pathways. The interplay of different functional groups within the molecule is pivotal for its potential bioactivity. Furthermore, the chloride ion in this compound may enhance solubility properties, making it an attractive candidate for synthetic chemists aiming to optimize compound delivery in biological systems.

In summary, the study of 2-(4-methylpiperazin-4-ium-1-yl)imino-1-(4-phenylsulfanylphenyl)ethanone; chloride not only enriches our understanding of organic synthesis but also opens doors to innovative therapeutic strategies.