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2-(4-methylthiazol-5-yl)acetic acid

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Identification
Molecular formula
C6H7NO2S
CAS number
14171-00-3
IUPAC name
2-(4-methylthiazol-5-yl)acetic acid
State
State

At room temperature, 2-(4-methylthiazol-5-yl)acetic acid is in a solid state, which is typical for most small organic acids.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
157.19g/mol
Molar mass
157.1910g/mol
Density
1.3000g/cm3
Appearence

2-(4-methylthiazol-5-yl)acetic acid typically appears as a white to off-white crystalline powder. Its appearance is quite similar to many other organic acid compounds, presenting a solid structure at room temperature.

Comment on solubility

Solubility of 2-(4-methylthiazol-5-yl)acetic Acid

2-(4-methylthiazol-5-yl)acetic acid, often recognized for its unique chemical structure, exhibits interesting solubility characteristics. When evaluating solubility, it is essential to consider the following factors:

  • Polarity: The presence of the carboxylic acid group contributes to the polarity of the molecule, enhancing its ability to interact with polar solvents like water.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the -COOH group may facilitate solubility in aqueous solutions, allowing 2-(4-methylthiazol-5-yl)acetic acid to dissolve effectively.
  • Organic Solvents: This compound may also show solubility in a variety of organic solvents such as ethanol or dimethyl sulfoxide (DMSO), providing versatility for laboratory applications.

Furthermore, it is worth noting that the solubility can be greatly influenced by:

  • pH Levels: The ionization state of the carboxylic acid can vary with pH, potentially affecting its solubility in water.
  • Temperature: Generally, an increase in temperature can lead to enhanced solubility for many compounds.

In summary, 2-(4-methylthiazol-5-yl)acetic acid showcases a moderate to high solubility profile in both polar and certain non-polar solvents, making it a useful compound in various chemical contexts. As always, careful experimentation should be conducted to determine the exact solubility under specific conditions.

Interesting facts

Interesting Facts about 2-(4-methylthiazol-5-yl)acetic acid

2-(4-methylthiazol-5-yl)acetic acid is a fascinating compound that belongs to a category of organic acids. Here are some intriguing aspects of this compound:

  • Biological Significance: This compound is known to have potential pharmacological effects, making it a subject of interest in medicinal chemistry. Compounds with thiazole structures often exhibit remarkable antimicrobial and antifungal properties.
  • Thiazole Ring: The thiazole moiety in this molecule, specifically the 4-methylthiazole part, contributes to its unique chemical behavior. Thiazole rings are a vital framework in various biologically active compounds.
  • Applications: The properties of 2-(4-methylthiazol-5-yl)acetic acid make it suitable for applications in agricultural chemistry as a potential herbicide or pesticide. Its efficacy against certain pathogens has garnered attention in research.
  • Synthesis Challenges: The synthesis of this compound can entail specific challenges due to the sensitive nature of thiazole-containing structures. Careful consideration of reaction conditions is essential to ensure optimal yields.

As chemists delve deeper into the applications and properties of 2-(4-methylthiazol-5-yl)acetic acid, they uncover more possibilities and its role in advancing pharmaceutical and agricultural science. Its intriguing nature reflects the complexity and beauty of chemical compounds in our world.

Synonyms
5255-33-4
4-Methyl-5-thiazoleacetic acid
2-(4-methyl-1,3-thiazol-5-yl)acetic acid
5-THIAZOLEACETIC ACID, 4-METHYL-
BRN 0120919
EINECS 226-056-8
DTXSID50200538
4-27-00-04018 (Beilstein Handbook Reference)
DTXCID80123029
bhywreoeqycksc-uhfffaoysa-n
2-(4-Methyl-5-thiazolyl)acetic Acid
2-(4-Methylthiazol-5-yl)acetic acid
Acide methyl-4 thiazole-acetique-5
MFCD01681551
_x000D_2-(4-Methyl-5-thiazolyl)acetic Acid
4-Methylthiazol-5-acetic acid
Acide methyl-4 thiazole-acetique-5 [French]
2-(4-Methyl-5-thiazolyl)aceticAcid
4-methylthiazole-5-acetic-acid
SCHEMBL2208741
CHEBI:185905
FAA25533
AC1428
AKOS006276495
AB09733
?2-(4-Methyl-5-thiazolyl)acetic Acid
AC-13449
CS-11918
DA-28115
SY033094
(4-Methyl-1,3-thiazol-5-yl)acetic acid
(4-Methyl-1,3-thiazol-5-yl)acetic acid #
CS-0308286
NS00032527
EN300-1139372